Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAF1 | P04049 | 2/20 | 0.45 |
| ▸ | BRAF | P15056 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27866914 | 0.83 | MAPT (0.51) | MAPTGSK3BSMN1; SMN2RAB9ATP53 | |
| SCHEMBL3784845 | 0.83 | MAPT (0.51) | MAPTGSK3BSMN1; SMN2RAB9ATP53 | |
| SCHEMBL17602322 | 0.78 | MAPT (0.45) | MAPTGSK3BSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL27455977 | 0.78 | CHRNB2 (0.61) | — | |
| SCHEMBL1853814 | 0.78 | MAPT (0.67) | MAPTSMN1; SMN2RAB9ATP53NPC1 | |
| SCHEMBL16583818 | 0.78 | KMO (0.61) | MAPTSMN1; SMN2ALDH1A1HPGDMAPK1 | |
| SCHEMBL31706768 | 0.77 | KMO (0.60) | MAPTGSK3BSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL686827 | 0.77 | KMO (0.60) | MAPTGSK3BSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL12205229 | 0.77 | LRRK2 (0.51) | MAPTSMN1; SMN2RAB9ATP53NPC1 | |
| SCHEMBL16106995 | 0.77 | GPR183 (0.59) | MAPTSMN1; SMN2RAB9ATP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065369-A1 | UREA COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2009-06-03 | — | — | EP | disclosed |