SCHEMBL9510216

SCHEMBL9510216

N[C@@H](CO)C1(C(=O)O)CC1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 1/20 0.32
GRM1 Q13255 2/20 0.31
USP2 O75604 1/20 0.31
SLCO1B1 Q9Y6L6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1161505 0.79 FFAR3 (0.39) SLC1A1
SCHEMBL3664521 0.71 SLC6A4 (0.36) SLC1A1USP2
SCHEMBL3989202 0.71 FFAR3 (0.36) SLC1A1
SCHEMBL179715 0.70 GRM1 (0.48) SLC1A1GRM1
SCHEMBL669743 0.70
SCHEMBL1110989 0.70 GRM1 (0.48) SLC1A1GRM1
SCHEMBL3195355 0.70 GRM1 (0.48) SLC1A1GRM1
SCHEMBL5667980 0.70 SLC6A4 (0.39) SLC1A1USP2
Hydrochloric Acid SCHEMBL1285236 0.70
Hydrochloric Acid SCHEMBL5665595 0.69 SLC6A4 (0.38) SLC1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0363994-B1 (2R,3S,4S)-ALPHA-(CARBOXYCYCLOPROPYL)GLYCINE SUNTORY LIMITED (JP) 1993-09-22 EP claimed
EP-0363994-A2 (2R,3S,4S)-alpha-(carboxycyclopropyl)glycine SUNTORY LIMITED (JP) 1990-04-18 EP claimed
EP-0363994-B1 (2R,3S,4S)-ALPHA-(CARBOXYCYCLOPROPYL)GLYCINE SUNTORY LIMITED (JP) 1993-09-22 EP disclosed
US-5068412-A Nervous system disorders such as treatment of epilepsy or Huntington's chorea SUNTORY LIMITED (JP) 1991-11-26 US disclosed
EP-0363994-A2 (2R,3S,4S)-alpha-(carboxycyclopropyl)glycine SUNTORY LIMITED (JP) 1990-04-18 EP disclosed