Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028624 | 0.80 | GAA (0.31) | — | |
| SCHEMBL5566940 | 0.77 | KMT2A (0.33) | — | |
| SCHEMBL11358289 | 0.77 | POLB (0.39) | CA2CA4 | |
| SCHEMBL358784 | 0.77 | GAA (0.42) | — | |
| SCHEMBL2515959 | 0.75 | NPC1 (0.45) | CA2 | |
| SCHEMBL2349664 | 0.75 | HTR2A (0.31) | — | |
| SCHEMBL6683483 | 0.75 | CA2 (0.34) | CA2CA4 | |
| SCHEMBL27829826 | 0.75 | — | — | |
| SCHEMBL219318 | 0.72 | GAA (0.42) | — | |
| SCHEMBL1526163 | 0.72 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064192-A2 | COMPOUNDS AND METHODS FOR INHIBITING THE INTERACTION OF BCL PROTEINS WITH BINDING PARTNERS | Infinity Discovery, Inc. (US) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008024337-A2 | COMPOUNDS AND METHODS FOR INHIBITING THE INTERACTION OF BCL PROTEINS WITH BINDING PARTNERS | INFINITY DISCOVERY, INC. (US) | 2008-02-28 | — | — | WO | disclosed |