Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654257 | 0.86 | APP (0.46) | SCN5ACYP1A2MAOARAB9AAPP | |
| SCHEMBL18394327 | 0.81 | ABCB11 (0.47) | SCN5AKDM4EAPPMAPTGAA | |
| SCHEMBL6318640 | 0.81 | HRH3 (0.46) | PHLPP2LMNASCN5ACYP1A2MAOA | |
| SCHEMBL4854821 | 0.78 | KCNH3 (0.49) | SCN5AMAPK1KDM4ERAB9AAPP | |
| SCHEMBL147856 | 0.78 | APP (0.42) | LMNACYP1A2MAOAKDM4ERAB9A | |
| SCHEMBL3856688 | 0.78 | DRD3 (0.44) | LMNASCN5ACYP1A2MAOACNR1 | |
| SCHEMBL15585738 | 0.77 | PTGER4 (0.42) | PHLPP2MAPK1KDM4EUSP2MAPT | |
| SCHEMBL11792842 | 0.77 | CYP3A4 (0.43) | LMNASCN5ACYP1A2MAOACNR1 | |
| SCHEMBL4848681 | 0.76 | KCNH3 (0.50) | MAPK1KDM4ERAB9AAPPMAPT | |
| SCHEMBL6650216 | 0.75 | APP (0.43) | SCN5AMAOAAPPMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1568683-B1 | Secondary, N-alkylaminated para-phenylenediamines, compositions for dyeing keratinic fibres containing them, processes using this compositions and uses thereof | OREAL (FR) | 2009-05-27 | — | — | EP | claimed |
| US-7338536-B2 | N-alkylamino secondary para-phenylenediamine, composition for dyeing keratin fibers comprising such a para-phenylenediamine, processes using this composition and uses thereof | L'OREAL S. A. (FR) | 2008-03-04 | — | — | US | claimed |
| US-20060026772-A1 | N-alkylamino secondary para-phenylenediamine, composition for dyeing keratin fibers comprising such a para-phenylenediamine, processes using this composition and uses thereof | L'OREAL | 2006-02-09 | — | — | US | claimed |
| EP-1568683-A2 | Secondary, N-alkylaminated para-phenylenediamines, compositions for dyeing keratinic fibres containing them, processes using this compositions and uses thereof | L'OREAL (FR) | 2005-08-31 | — | — | EP | claimed |
| EP-1568683-B1 | Secondary, N-alkylaminated para-phenylenediamines, compositions for dyeing keratinic fibres containing them, processes using this compositions and uses thereof | OREAL (FR) | 2009-05-27 | — | — | EP | disclosed |
| US-7338536-B2 | N-alkylamino secondary para-phenylenediamine, composition for dyeing keratin fibers comprising such a para-phenylenediamine, processes using this composition and uses thereof | L'OREAL S. A. (FR) | 2008-03-04 | — | — | US | disclosed |
| US-7338536-B2 | N-alkylamino secondary para-phenylenediamine, composition for dyeing keratin fibers comprising such a para-phenylenediamine, processes using this composition and uses thereof | L'OREAL S. A. (FR) | 2008-03-04 | — | — | US | disclosed |
| US-7338536-B2 | N-alkylamino secondary para-phenylenediamine, composition for dyeing keratin fibers comprising such a para-phenylenediamine, processes using this composition and uses thereof | L'OREAL S. A. (FR) | 2008-03-04 | — | — | US | disclosed |
| US-20060026772-A1 | N-alkylamino secondary para-phenylenediamine, composition for dyeing keratin fibers comprising such a para-phenylenediamine, processes using this composition and uses thereof | L'OREAL | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060026772-A1 | N-alkylamino secondary para-phenylenediamine, composition for dyeing keratin fibers comprising such a para-phenylenediamine, processes using this composition and uses thereof | KRT18, CDC73, PRKDC | PHLPP2 1980/4885LMNA 176/4885SCN5A 207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.