Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.50 |
| ▸ | PIM1 | P11309 | 2/20 | 0.50 |
| ▸ | FLT3 | P36888 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | PAK4 | O96013 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13512629 | 0.84 | ALDH1A1 (0.63) | AHRNR4A2CYP2A6LMNAHPGD | |
| SCHEMBL12338439 | 0.78 | ALDH1A1 (0.65) | AHRNR4A2HPGDAURKAALDH1A1 | |
| SCHEMBL1885355 | 0.78 | ALDH1A1 (0.71) | AHRNR4A2LMNAHPGDCHEK1 | |
| SCHEMBL12338438 | 0.76 | ALDH1A1 (0.63) | AHRNR4A2HPGDAURKAALDH1A1 | |
| SCHEMBL668615 | 0.76 | AHR (0.53) | AHRLMNAHPGDALDH1A1GPR84 | |
| SCHEMBL6935037 | 0.76 | ALDH1A1 (0.56) | NR4A2LMNAHPGDALDH1A1CCR8 | |
| SCHEMBL1880534 | 0.76 | PDE10A (0.49) | HPGDALDH1A1CCR8HSD17B10KMT2A | |
| SCHEMBL14242737 | 0.76 | NPSR1 (0.53) | LMNAHPGDCHEK1ALDH1A1CCR8 | |
| SCHEMBL1430366 | 0.76 | ALDH1A1 (0.48) | AHRNR4A2PDGFRBPDGFRAFLT1 | |
| SCHEMBL20675600 | 0.73 | ALDH1A1 (0.53) | LMNAHPGDPIM1DAPK3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12617767-B2 | Crystalline forms of somatostatin modulators | Crinetics Pharmaceuticals, Inc. (US) | 2026-05-05 | — | — | US | disclosed |
| EP-4608808-A1 | SOMATOSTATIN RECEPTOR 2 AGONISTS AND USES THEREOF | Basecamp Bio Inc. (KY) | 2025-09-03 | — | — | EP | disclosed |
| US-20240376067-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | Crinetics Pharmaceuticals, Inc. | 2024-11-14 | — | — | US | disclosed |
| WO-2024089668-A1 | SOMATOSTATIN RECEPTOR 2 AGONISTS AND USES THEREOF | BASECAMP BIO INC. (KY) | 2024-05-02 | — | — | WO | disclosed |
| CN-116377457-A | Electrochemical synthesis method of halogenated quinoline-4 (1H) -ketone derivative | 桂林理工大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-111868049-B | Process for preparing somatostatin modulators | 克林提克斯医药股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| WO-2023060255-A1 | QUINOLONE ALKYL AMINES AS NOVEL SEROTONIN 2A RECEPTOR (5HT2AR) AGONISTS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-04-13 | — | — | WO | disclosed |
| EP-4092018-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | Crinetics Pharmaceuticals, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |
| US-20220267295-A1 | CRYSTALLINE FORMS OF SOMATOSTATIN MODULATORS | Crinetics Pharmaceuticals, Inc. | 2022-08-25 | — | — | US | disclosed |
| EP-3999509-A1 | CRYSTALLINE FORMS OF SOMATOSTATIN MODULATORS | Crinetics Pharmaceuticals, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |
| WO-2019143718-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | Crinetics Pharmaceuticals, Inc. (US) | 2019-07-25 | — | — | WO | disclosed |
| US-20190218202-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | Crinetics Pharmaceuticals, Inc. | 2019-07-18 | — | — | US | disclosed |
| US-20190218202-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | Crinetics Pharmaceuticals, Inc. | 2019-07-18 | — | — | US | disclosed |
| US-10301305-B2 | Heteroaromatic derivatives and their use as pharmaceuticals | MUTABILIS (FR) | 2019-05-28 | — | — | US | disclosed |
| EP-3110803-B1 | HETEROAROMATIC DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | MUTABILIS (FR) | 2018-07-11 | — | — | EP | disclosed |
| US-20170015661-A1 | HETEROAROMATIC DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | MUTABILIS (FR) | 2017-01-19 | — | — | US | disclosed |
| EP-3110803-A1 | HETEROAROMATIC DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | Mutabilis (FR) | 2017-01-04 | — | — | EP | disclosed |
| WO-2015128333-A1 | HETEROAROMATIC DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | LABORATOIRE BIODIM (FR) | 2015-09-03 | — | — | WO | disclosed |
| EP-2913330-A1 | Condensed derivatives of imidazole useful as pharmaceuticals | LABORATOIRE BIODIM (FR) | 2015-09-02 | — | — | EP | disclosed |
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267295-A1 | CRYSTALLINE FORMS OF SOMATOSTATIN MODULATORS | SSTR5, SSTR4, SSTR3 | AHR 4209/4885NR4A2 2182/4885CYP2A6 3305/4885 |
| US-12617767-B2 | Crystalline forms of somatostatin modulators | IAPP, SSTR2, SSTR3 | AHR 4035/4885NR4A2 1782/4885CYP2A6 3147/4885 |
| US-20190218202-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | SSTR5, SSTR4, SSTR2 | AHR 3334/4885NR4A2 2897/4885CYP2A6 2815/4885 |
| US-20240376067-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | SSTR5, SSTR4, SSTR2 | AHR 3334/4885NR4A2 2897/4885CYP2A6 2815/4885 |
| US-20170015661-A1 | HETEROAROMATIC DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | MSR1, IFNAR1, NOD2 | AHR 32/4885NR4A2 1292/4885CYP2A6 138/4885 |
| US-10301305-B2 | Heteroaromatic derivatives and their use as pharmaceuticals | MSR1, IFNAR1, NOD2 | AHR 32/4885NR4A2 1292/4885CYP2A6 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.