Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673734 | 0.78 | ADORA2A (0.51) | SLC29A1ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL41683 | 0.78 | KDM4E (0.47) | SLC29A1ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL3819352 | 0.77 | SLC29A1 (0.47) | SLC29A1ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL6137853 | 0.77 | ALDH1A1 (0.46) | SLC29A1ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL9671653 | 0.76 | ADORA2A (0.49) | SLC29A1ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL9671648 | 0.76 | ADORA2A (0.48) | SLC29A1ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL9670839 | 0.75 | ADORA2A (0.42) | SLC29A1ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL9670914 | 0.74 | ADORA2A (0.44) | SLC29A1ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL9670813 | 0.74 | ADORA2A (0.49) | SLC29A1ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL8029815 | 0.74 | ALDH1A1 (0.43) | SLC29A1ADORA2AADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061316-A2 | AZOLE NUCLEOSIDES AND USE AS INHIBITORS OF RNA AND DNA VARIAL POLYMERASES | Southern Research Institute (US) | 2009-05-27 | — | — | EP | claimed |
| WO-2008067002-A2 | AZOLE NUCLEOSIDES AND USE AS INHIBITORS OF RNA AND DNA VARIAL POLYMERASES | SOUTHERN RESEARCH INSTITUTE (US) | 2008-06-05 | — | — | WO | claimed |