Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755513 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| SCHEMBL10781630 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| SCHEMBL10781628 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| SCHEMBL3989914 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| SCHEMBL8714724 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| SCHEMBL6275649 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| SCHEMBL106017 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| SCHEMBL9755481 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| Hydrochloric Acid SCHEMBL9344359 | 0.98 | HSD17B10 (0.59) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| Hydrochloric Acid SCHEMBL11483489 | 0.98 | HSD17B10 (0.59) | HSD17B10KDM4ETDP1TSHRCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187209-B1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS | F. HOFFMANN-LA ROCHE AG (CH) | 1992-01-08 | — | — | EP | claimed |
| US-4716227-A | Process for manufacturing cephalosporin esters | HOFFMANN-LA ROCHE INC. (US) | 1987-12-29 | — | — | US | claimed |
| EP-0187209-A2 | Process for the preparation of cephalosporins | F. HOFFMANN-LA ROCHE AG (CH) | 1986-07-16 | — | — | EP | claimed |
| US-3932392-A | DICYCLOHEXYLAMINE, DIISOPROPYLAMINE | BRISTOL-MYERS COMPANY (US) | 1976-01-13 | — | — | US | claimed |
| JP-59076087-A | — | — | None | — | — | JP | disclosed |
| JP-58088386-A | — | — | None | — | — | JP | disclosed |
| US-20090221815-A1 | PROCESSES FOR THE PREPARATION OF CEPHEM DERIVATIVES | CJ CHEILJEDANG CORPORATION (KR) | 2009-09-03 | — | — | US | disclosed |
| US-7544797-B2 | Processes for the preparation of cephem derivatives | CJ CHEILJEDANG CORPORATION (KR) | 2009-06-09 | — | — | US | disclosed |
| EP-1678186-A4 | PROCESSES FOR THE PREPARATION OF CEPHEM DERIVATIVES | CJ CORP (KR) | 2007-04-25 | — | — | EP | disclosed |
| US-20070060747-A1 | Processes for the preparation of cephem derivatives | CJ CORPORATION (KR) | 2007-03-15 | — | — | US | disclosed |
| EP-1678186-A1 | PROCESSES FOR THE PREPARATION OF CEPHEM DERIVATIVES | CJ Corporation (KR) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042543-A1 | PROCESSES FOR THE PREPARATION OF CEPHEM DERIVATIVES | CJ CORPORATION (KR) | 2005-05-12 | — | — | WO | disclosed |
| US-3944545-A | Process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1976-03-16 | — | — | US | disclosed |
| US-3943127-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1976-03-09 | — | — | US | disclosed |
| US-3943128-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1976-03-09 | — | — | US | disclosed |
| US-3939266-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |
| US-3932392-A | DICYCLOHEXYLAMINE, DIISOPROPYLAMINE | BRISTOL-MYERS COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
| US-3932392-A | DICYCLOHEXYLAMINE, DIISOPROPYLAMINE | BRISTOL-MYERS COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
| US-3932465-A | ANTIBIOTIC | CIBA-GEIGY CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |
| US-3873523-A | Derivatives of ampicillin | PARKE DAVIS & CO | 1975-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060747-A1 | Processes for the preparation of cephem derivatives | CEP170, HAMP, NISCH | HSD17B10 1307/4885KDM4E 3237/4885TDP1 3736/4885 |
| US-20090221815-A1 | PROCESSES FOR THE PREPARATION OF CEPHEM DERIVATIVES | CEP170, HAMP, NISCH | HSD17B10 1307/4885KDM4E 3237/4885TDP1 3736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.