Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755513 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| SCHEMBL10781630 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| SCHEMBL3989912 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| SCHEMBL10781628 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| SCHEMBL3989914 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| SCHEMBL8714724 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| SCHEMBL6275649 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| SCHEMBL9755481 | 1.00 | HSD17B10 (0.60) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| Hydrochloric Acid SCHEMBL9344359 | 0.98 | HSD17B10 (0.59) | HSD17B10KDM4ETDP1TSHRCACNA1B | |
| Hydrochloric Acid SCHEMBL11483489 | 0.98 | HSD17B10 (0.59) | HSD17B10KDM4ETDP1TSHRCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3965098-A | Intermediates for preparing cephalosporins and methods of production | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-06-22 | — | — | US | claimed |
| US-12535484-B2 | Autoantibodies and autoantibody-autoantigen complexes as biomarkers of small cell lung cancer | FRED HUTCHINSON CANCER CENTER (US) | 2026-01-27 | — | — | US | disclosed |
| US-12344653-B2 | Antigen binding molecules for small cell lung cancer | FRED HUTCHINSON CANCER CENTER (US) | 2025-07-01 | — | — | US | disclosed |
| CN-118308392-A | Preparation method and application of G-7-ADCA producing strain | 中国科学院天津工业生物技术研究所 | 2024-07-09 | — | — | CN | disclosed |
| CN-118185913-A | Paracoccus-derived amidase and application of mutant thereof | 河北科技大学 | 2024-06-14 | — | — | CN | disclosed |
| US-20220235093-A1 | BILE SALT HYDROLASE PROBE AND METHOD OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2022-07-28 | — | — | US | disclosed |
| CN-112852913-B | Deacetoxycephalosporin C synthetase mutant and application thereof in synthesis of beta-lactam antibiotic parent nucleus | 中国科学院天津工业生物技术研究所 | 2021-12-10 | — | — | CN | disclosed |
| US-11155573-B2 | Bile salt hydrolase probe and method of making and using the same | BATTELLE MEMORIAL INSTITUTE (US) | 2021-10-26 | — | — | US | disclosed |
| CN-112479909-B | Extraction and recovery method of p-hydroxyphenylglycine | 河南大学 | 2021-10-12 | — | — | CN | disclosed |
| CN-112852913-A | Deacetoxycephalosporin C synthetase mutant and application thereof in synthesis of beta-lactam antibiotic parent nucleus | 中国科学院天津工业生物技术研究所 | 2021-05-28 | — | — | CN | disclosed |
| US-4118562-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1978-10-03 | — | — | US | disclosed |
| US-4109084-A | ANTIBIOTICS, BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1978-08-22 | — | — | US | disclosed |
| US-4093802-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1978-06-06 | — | — | US | disclosed |
| US-4093804-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1978-06-06 | — | — | US | disclosed |
| US-4045438-A | Cephalosporin antibiotics | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1977-08-30 | — | — | US | disclosed |
| US-4031083-A | Cephalosporin antibiotics | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1977-06-21 | — | — | US | disclosed |
| US-4026887-A | Cephalosporin antibiotics | YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) | 1977-05-31 | — | — | US | disclosed |
| US-3994875-A | CEPHALOSPORINS, PENICILLINS | YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) | 1976-11-30 | — | — | US | disclosed |
| US-3975385-A | 7-Trichloroacetamido-3-desacetoxy-cephalosporanic acid esters | RHONE-POULENC S.A. (FR) | 1976-08-17 | — | — | US | disclosed |
| US-3948904-A | ANTIBIOTICS | YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12535484-B2 | Autoantibodies and autoantibody-autoantigen complexes as biomarkers of small cell lung cancer | SNAP23, SMPD3, SPCS3 | HSD17B10 3478/4885KDM4E 3610/4885TDP1 1545/4885 |
| US-11155573-B2 | Bile salt hydrolase probe and method of making and using the same | BCHE, NR1H4, NCEH1 | HSD17B10 156/4885KDM4E 3388/4885TDP1 1299/4885 |
| US-20220235093-A1 | BILE SALT HYDROLASE PROBE AND METHOD OF MAKING AND USING THE SAME | BCHE, NR1H4, NCEH1 | HSD17B10 156/4885KDM4E 3388/4885TDP1 1299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.