Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | IAPP | P10997 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952889 | 0.86 | GABRA1 (0.64) | GABRA1GABRB2IAPPLMNAALDH1A1 | |
| SCHEMBL3584443 | 0.81 | GABRA1 (0.56) | GABRA1GABRB2IAPPCDK2IDO1 | |
| SCHEMBL344347 | 0.80 | IAPP (0.69) | GABRA1GABRB2IAPPMAPTKDM4E | |
| SCHEMBL2697663 | 0.79 | TYR (0.57) | IAPPHPGDHSD17B10MAPTKDM4E | |
| SCHEMBL11220048 | 0.78 | GABRA1 (0.48) | GABRA1GABRB2IDO1HPGDHSD17B10 | |
| SCHEMBL29525444 | 0.78 | LMNA (0.55) | GABRA1GABRB2IDO1LMNAMAPT | |
| SCHEMBL22778226 | 0.78 | LMNA (0.55) | GABRA1GABRB2IDO1LMNAMAPT | |
| SCHEMBL10962332 | 0.77 | GABRA1 (0.38) | GABRA1GABRB2CDK2IDO1CYP1A2 | |
| SCHEMBL3955098 | 0.77 | IDO1 (0.59) | GABRA1GABRB2IDO1MEN1KMT2A | |
| SCHEMBL70065 | 0.76 | GABRA1 (0.76) | GABRA1GABRB2IAPPCDK2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765821-A4 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | FOB SYNTHESIS INC (US) | 2009-05-20 | — | — | EP | disclosed |
| EP-1765821-A2 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | FOB Synthesis, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005123069-A2 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | FOB SYNTHESIS, INC. (US) | 2005-12-29 | — | — | WO | disclosed |