Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80655 | 0.80 | — | — | |
| SCHEMBL1806242 | 0.80 | — | — | |
| SCHEMBL1806245 | 0.80 | — | — | |
| SCHEMBL28608405 | 0.80 | CA2 (0.31) | — | |
| SCHEMBL5417839 | 0.79 | DPP4 (0.30) | — | |
| SCHEMBL18341048 | 0.78 | ENPEP (0.32) | — | |
| SCHEMBL68246 | 0.78 | CACNA2D1 (0.32) | ADRA1A | |
| SCHEMBL68248 | 0.78 | CACNA2D1 (0.32) | ADRA1A | |
| SCHEMBL18341050 | 0.78 | ENPEP (0.32) | — | |
| SCHEMBL18341245 | 0.78 | ENPEP (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101604-B2 | Alpha carbolines and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-01-24 | — | — | US | disclosed |