Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 4/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3996046 | 0.98 | CHRM5 (0.32) | GNAO1GNAI3GNAI1 | |
| SCHEMBL3997166 | 0.96 | GNAO1 (0.33) | GNAO1GNAI3GNAI1 | |
| SCHEMBL19139233 | 0.84 | GNAO1 (0.30) | GNAO1 | |
| SCHEMBL3994096 | 0.84 | CYP1A2 (0.38) | GNAO1 | |
| SCHEMBL18682741 | 0.78 | HTT (0.30) | — | |
| SCHEMBL23080343 | 0.73 | HTT (0.36) | — | |
| SCHEMBL7450744 | 0.73 | ARG1 (0.32) | — | |
| SCHEMBL19033715 | 0.72 | MEN1 (0.33) | — | |
| SCHEMBL21276531 | 0.72 | — | — | |
| SCHEMBL14212686 | 0.70 | KDM4E (0.39) | GNAO1GNAI3GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606288-B1 | BENZENESULPHONAMIDE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF FOR TREATMENT OF PAIN | FOURNIER LAB SA (FR) | 2009-06-03 | — | — | EP | disclosed |
| EP-1606288-A1 | BENZENESULPHONAMIDE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF FOR TREATMENT OF PAIN | LABORATOIRES FOURNIER S.A. (FR) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004087700-A1 | BENZENESULPHONAMIDE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF FOR TREATMENT OF PAIN | LABORATOIRES FOURNIER S.A. (FR) | 2004-10-14 | — | — | WO | disclosed |