⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17163827 | 0.74 | MAPT (0.39) | — | |
| SCHEMBL7049757 | 0.72 | ACHE (0.38) | — | |
| SCHEMBL2973 | 0.72 | — | — | |
| SCHEMBL27551764 | 0.70 | — | — | |
| SCHEMBL19711915 | 0.70 | — | — | |
| SCHEMBL27282160 | 0.70 | — | — | |
| SCHEMBL9743951 | 0.69 | — | — | |
| SCHEMBL743480 | 0.69 | ACHE (0.31) | — | |
| SCHEMBL27460010 | 0.69 | ACHE (0.31) | — | |
| SCHEMBL9828749 | 0.69 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642918-B | Diosgenin derivative and preparation method and application thereof | 山东师范大学 | 2021-01-08 | — | — | CN | claimed |
| CN-110642918-A | Diosgenin derivative and preparation method and application thereof | 山东师范大学 | 2020-01-03 | — | — | CN | claimed |
| EP-2421837-A1 | PREPARATION OF C-PYRAZINE-METHYLAMINES | OSI Pharmaceuticals, LLC (US) | 2012-02-29 | — | — | EP | claimed |
| WO-2010123792-A1 | PREPARATION OF C-PYRAZINE-METHYLAMINES | OSI PHARMACEUTICALS, INC. (US) | 2010-10-28 | — | — | WO | claimed |
| US-20030065192-A1 | Antimicrobial compounds and methods of use | GHOSH TIRTHANKAR (US) | 2003-04-03 | — | — | US | claimed |
| EP-1223171-A1 | Antimicrobial 5-substituted-3-isothiazolone compounds and methods of use | Rohm and Haas (US) | 2002-07-17 | — | — | EP | claimed |
| CN-115181051-B | Preparation method of sulfoxide compound containing indole skeleton | 扬州大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-109906222-B | Allosteric corticotropin releasing factor receptor 1 (CRFR 1) antagonists that reduce P-TAU and improve cognition | 加利福尼亚大学董事会 | 2023-08-01 | — | — | CN | disclosed |
| CN-115181051-A | Preparation method of sulfoxide compound containing indole skeleton | 扬州大学 | 2022-10-14 | — | — | CN | disclosed |
| EP-3969444-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND DISORDERS | The Regents of the University of California (US) | 2022-03-23 | — | — | EP | disclosed |
| EP-3153023-B1 | BENZOXAZOLE KINASE INHIBITORS AND METHODS OF USE | TAKEDA PHARMACEUTICALS CO (JP) | 2022-03-16 | — | — | EP | disclosed |
| US-20210253566-A1 | CYTOCHROME P450 INHIBITORS AND USES THEREOF | ANGION BIOMEDICA CORP. | 2021-08-19 | — | — | US | disclosed |
| US-11077108-B2 | Allosteric corticotropin-releasing factor receptor 1 (CRFR1) antagonists that decrease p-tau and improve cognition | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-03 | — | — | US | disclosed |
| EP-0576199-A2 | Fungicidal and herbicidal triazoles | ROHM AND HAAS COMPANY (US) | 1993-12-29 | — | — | EP | disclosed |
| EP-0575122-A2 | Fungicidal (2-aryl-2-substituted) ethyl-1,2,4-triazoles | ROHM AND HAAS COMPANY (US) | 1993-12-22 | — | — | EP | disclosed |
| US-5264415-A | 1,2,4-Triazole derivatives | ROHM AND HAAS COMPANY (US) | 1993-11-23 | — | — | US | disclosed |
| US-5252594-A | Broad spectrum, systemic | ROHM AND HAAS COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| US-5216007-A | Fungicides | ROHM AND HAAS COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0076628-A2 | Novel substituted imidazoles and triazoles, fungicidal compositions containing them and the use of the novel compounds for combating fungi | ROHM AND HAAS COMPANY (US) | 1983-04-13 | — | — | EP | disclosed |
| US-4366165-A | 1 and 4-Arylcyanoalkyl-1,2,4-triazoles and fungicidal use | ROHM AND HAAS COMPANY (US) | 1982-12-28 | — | — | US | disclosed |