Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.50 |
| ▸ | CES1 | P23141 | 5/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 7/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781400 | 1.00 | FAAH (0.50) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL1862740 | 1.00 | FAAH (0.50) | FAAHCES1CES2MEN1CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL18424610 | 0.98 | FAAH (0.48) | FAAHCES1CES2MEN1CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL17848784 | 0.98 | FAAH (0.48) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL3777756 | 0.78 | FAAH (0.59) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL3787603 | 0.78 | FAAH (0.59) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL3415485 | 0.78 | FAAH (0.59) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL9435633 | 0.78 | FAAH (0.59) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL3778978 | 0.78 | FAAH (0.59) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL3777162 | 0.78 | FAAH (0.59) | FAAHCES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009074569-A1 | TARGETING AND THERAPEUTIC COMPOUNDS WITH A POLYPROLINE-COMPRISING SPACER AND GAS-FILLED MICROVESICLES COMPRISING SAID COMPOUNDS | BRACCO INTERNATIONAL BV (NL) | 2009-06-18 | — | — | WO | disclosed |