Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3996205 | 0.91 | PSMB5 (0.43) | PSMB5TRPM8HSP90AA1HSP90AB1PDK1 | |
| SCHEMBL6161238 | 0.83 | SLC2A1 (0.44) | SIRT2ABCB1TP53MAPTLPAR1 | |
| SCHEMBL4963925 | 0.82 | TRPM8 (0.49) | TRPM8TP53GAAMAPTMEN1 | |
| SCHEMBL4962717 | 0.82 | TRPM8 (0.53) | TRPM8TP53GAAMAPTTHRB | |
| SCHEMBL4962776 | 0.81 | TRPM8 (0.54) | PSMB5TRPM8TP53GAAMAPT | |
| SCHEMBL4963743 | 0.81 | TRPM8 (0.59) | TRPM8HSP90AA1HSP90AB1PDK1PDK2 | |
| SCHEMBL6160055 | 0.80 | SIRT2 (0.41) | PSMB5SIRT2ABCB1PPARAPPARD | |
| SCHEMBL6160047 | 0.78 | SIRT2 (0.39) | PSMB5SIRT2ABCB1PPARAPPARD | |
| SCHEMBL4963522 | 0.78 | PPARG (0.43) | TRPM8TP53MAPTLPAR1LPAR5 | |
| SCHEMBL4965244 | 0.76 | MAPT (0.46) | TRPM8TP53GAAMAPTPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521461-B2 | Benzoic acid derivatives as modulators of PPAR alpha and gamma | ASTRAZENECA AB (SE) | 2009-04-21 | — | — | US | disclosed |
| US-20050267149-A1 | Benzoic acid derivatives as modulators of ppar alpha and gamma | ASTRAZENECA AB (SE) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267149-A1 | Benzoic acid derivatives as modulators of ppar alpha and gamma | PPARG, NR4A1, NR0B1 | PSMB5 729/4885TRPM8 1046/4885HSP90AA1 1568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.