Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3997797 | 0.90 | NPC1 (0.46) | PLA2G1BATG4BNPC1TSPOLMNA | |
| SCHEMBL4629905 | 0.86 | LPAR1 (0.46) | TSPOALDH1A1KDM4ETRPM8HPGD | |
| SCHEMBL4965244 | 0.80 | MAPT (0.46) | NPC1TSPOMAPTHTTRAB9A | |
| SCHEMBL4630654 | 0.79 | TSPO (0.55) | TSPOLMNAALDH1A1KDM4EHTT | |
| SCHEMBL4629897 | 0.78 | LPAR1 (0.53) | TSPOTRPM8 | |
| SCHEMBL4630463 | 0.77 | LPAR1 (0.45) | NPC1TSPOLMNAFFAR4MAPT | |
| SCHEMBL5309541 | 0.76 | KMT2A (0.64) | PLA2G1BATG4BNPC1LMNAALDH1A1 | |
| SCHEMBL10411181 | 0.76 | SLC6A3 (0.58) | PLA2G1BATG4BLMNAFFAR4MAPT | |
| SCHEMBL3996243 | 0.76 | TP53 (0.48) | NPC1TSPOMAPTRAB9ATRPM8 | |
| Tert-Butylamine SCHEMBL5309305 | 0.74 | LPAR1 (0.49) | TSPOALDH1A1MAPTTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521461-B2 | Benzoic acid derivatives as modulators of PPAR alpha and gamma | ASTRAZENECA AB (SE) | 2009-04-21 | — | — | US | disclosed |
| US-20050267149-A1 | Benzoic acid derivatives as modulators of ppar alpha and gamma | ASTRAZENECA AB (SE) | 2005-12-01 | — | — | US | disclosed |
| EP-1517680-A1 | BENZOIC ACID DERIVATIVES AS MODULATORS OF PPAR ALPHA AND GAMMA | Astrazeneca AB (SE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000295-A1 | BENZOIC ACID DERIVATIVES AS MODULATORS OF PPAR ALPHA AND GAMMA | ASTRAZENECA AB (SE) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267149-A1 | Benzoic acid derivatives as modulators of ppar alpha and gamma | PPARG, NR4A1, NR0B1 | PLA2G1B 2559/4885ATG4B 2733/4885NPC1 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.