Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185716 | 0.94 | PHGDH (0.47) | ITGB3ITGA2BKMT2APHGDHTDP1 | |
| SCHEMBL4000787 | 0.90 | ITGB3 (0.52) | ITGB3ITGA2BKMT2ATDP1ALDH1A1 | |
| SCHEMBL8191172 | 0.87 | PHGDH (0.47) | ITGB3ITGA2BKMT2APHGDHHTT | |
| SCHEMBL8186175 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BKMT2ATDP1ALDH1A1 | |
| SCHEMBL4000321 | 0.86 | GAA (0.50) | KMT2APHGDHTDP1HTTLMNA | |
| SCHEMBL11489916 | 0.83 | KDM1A (0.48) | ITGB3ITGA2BKMT2ATDP1LMNA | |
| SCHEMBL4462112 | 0.83 | KMT2A (0.48) | KMT2ATDP1HTTLMNAHTR1A | |
| SCHEMBL14084962 | 0.80 | MAPT (0.48) | ITGB3ITGA2BALDH1A1HTR1AHTR7 | |
| SCHEMBL24207657 | 0.80 | L3MBTL3 (0.43) | ITGB3ITGA2BKMT2AALDH1A1KDM1A | |
| SCHEMBL1906248 | 0.78 | GAA (0.52) | PHGDHTDP1LMNAALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606288-B1 | BENZENESULPHONAMIDE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF FOR TREATMENT OF PAIN | FOURNIER LAB SA (FR) | 2009-06-03 | — | — | EP | disclosed |