Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007071 | 0.92 | MEN1 (0.37) | ABCG2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL4001884 | 0.88 | ABCB1 (0.37) | ABCB1ABCG2KDM4EALDH1A1MAPT | |
| SCHEMBL3996885 | 0.87 | ABCB1 (0.39) | ABCB1ABCG2KDM4EALDH1A1MAPT | |
| SCHEMBL4003027 | 0.86 | ALDH1A1 (0.40) | ABCB1ABCG2KDM4EALDH1A1MAPT | |
| SCHEMBL4004837 | 0.82 | ABCG2 (0.39) | ABCB1ABCG2KDM4EALDH1A1MAPT | |
| SCHEMBL4002142 | 0.80 | KMT2A (0.44) | ABCG2ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL4007345 | 0.78 | MEN1 (0.38) | ABCG2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL3007512 | 0.75 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTMEN1CYP3A4 | |
| SCHEMBL3998431 | 0.74 | LMNA (0.40) | ALDH1A1MEN1CYP3A4KMT2AHPGD | |
| SCHEMBL2997489 | 0.73 | ALDH1A1 (0.45) | ABCB1ABCG2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | disclosed |