SCHEMBL4000461

SCHEMBL4000461

CCCCCCCCCCCCCCCC(=O)NCCC(=O)O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.76
CNR1 P21554 2/20 0.76
CNR2 P34972 2/20 0.76
PLA2G2A P14555 1/20 0.68
EPHX2 P34913 3/20 0.68
DNM1 Q05193 1/20 0.62
KDM4E B2RXH2 1/20 0.62
CASP2 P42575 1/20 0.62
PPARG P37231 4/20 0.61
PPARD Q03181 4/20 0.61
PPARA Q07869 4/20 0.61
TSHR P16473 3/20 0.61
GPR84 Q9NQS5 3/20 0.61
HDAC11 Q96DB2 3/20 0.61
ALDH1A1 P00352 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
SLC22A6 Q4U2R8 1/20 0.61
SLC22A8 Q8TCC7 1/20 0.61
TLR2 O60603 1/20 0.61
MEN1 O00255 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL532448 1.00 FAAH (0.76) FAAHCNR1CNR2PLA2G2AEPHX2
SCHEMBL531436 1.00 FAAH (0.76) FAAHCNR1CNR2PLA2G2AEPHX2
SCHEMBL9828949 1.00 FAAH (0.76) FAAHCNR1CNR2PLA2G2AEPHX2
SCHEMBL9193102 1.00 FAAH (0.76) FAAHCNR1CNR2PLA2G2AEPHX2
SCHEMBL9256918 1.00 FAAH (0.76) FAAHCNR1CNR2PLA2G2AEPHX2
SCHEMBL3990517 1.00 FAAH (0.76) FAAHCNR1CNR2PLA2G2AEPHX2
SCHEMBL5964111 1.00 FAAH (0.76) FAAHCNR1CNR2PLA2G2AEPHX2
SCHEMBL31529340 1.00 FAAH (0.76) FAAHCNR1CNR2PLA2G2AEPHX2
SCHEMBL7147169 1.00 FAAH (0.76) FAAHCNR1CNR2PLA2G2AEPHX2
SCHEMBL688844 0.98 FAAH (0.73) FAAHCNR1CNR2PLA2G2AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4749515-A SULFOSUCCINIC ACID MONOESTERS, ACYLATED PEPTIDES; FOAMING, RINSING PROPERTIES LION CORPORATION (JP) 1988-06-07 US claimed
EP-3468983-A1 PEPTIDE, COMPOSITION COMPRISING SAID PEPTIDE AND USES THEREOF, IN PARTICULAR COSMETIC USES SEDERMA (FR) 2019-04-17 EP disclosed
WO-2017216177-A1 PEPTIDE, COMPOSITION COMPRISING SAID PEPTIDE AND USES THEREOF, IN PARTICULAR COSMETIC USES SEDERMA (FR) 2017-12-21 WO disclosed
EP-3256102-A1 PEPTIDIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES OF SAID COMPOUNDS, IN PARTICULAR COSMETIC USES Sederma (FR) 2017-12-20 EP disclosed
EP-3233210-A1 TRIPEPTIDES, COMPOSITIONS THEREOF AND THEIR COSMETIC USES Sederma (FR) 2017-10-25 EP disclosed
EP-3065697-A1 OPTICALLY CLEAR ACYL-ISETHIONATE AQUEOUS CONCENTRATE FOR COSMETIC USE Clariant International AG (CH) 2016-09-14 EP disclosed
US-20160243014-A1 Optically Clear Acyl-Isethionate Aqueous Concentrate for Cosmetic Use CLARIANT INTERNATIONAL AG (CH) 2016-08-25 US disclosed
WO-2016097966-A1 TRIPEPTIDES, COMPOSITIONS THEREOF AND THEIR COSMETIC USES SEDERMA (FR) 2016-06-23 WO disclosed
WO-2016097965-A1 PEPTIDIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES OF SAID COMPOUNDS, IN PARTICULAR COSMETIC USES SEDERMA (FR) 2016-06-23 WO disclosed
CN-105431512-A Liquid cleaning agent composition FUJIFILM CORP 2016-03-23 CN disclosed
US-6359008-B1 IMPROVED BIOAVAILABILITY OF DRUGS AND NUTRIENTS BY PERMEABILIZING CELL MEMBRANES OF ORGANISMS, IN PARTICULAR ANIMALS AND FISH; PREFERABLY CONTAIN A LONG CHAIN ALKYL OR ALKENYL GROUP, SUCH AS A PALMITOYL OR OLEATE GROUP LOVESGROVE RESEARCH LIMITED (GB) 2002-03-19 US disclosed
WO-2001042409-A1 STABLE, HIGH GLYCEROL LIQUIDS COMPRISING N-ACYL AMINO ACIDS AND/OR SALTS UNILEVER PLC (GB) 2001-06-14 WO disclosed
EP-0799188-B1 AMIDES OF MONO AND DICARBOXYLIC ACIDS WITH GLYCOSAMINES, SELECTIVELY ACTIVE ON THE CANNABINOID PERIPHERAL RECEPTOR LIFEGROUP SPA (IT) 1999-09-15 EP disclosed
WO-1999044986-A1 ACYLATED AMINOACIDS FOR INCREASING THE UPTAKE OF SELECTED SUBSTANCES BY ORGANISMS LOVESGROVE RESEARCH LIMITED (GB) 1999-09-10 WO disclosed
EP-0799188-A2 AMIDES OF MONO AND BICARBOXYLIC ACIDS WITH AMINO ACIDS OR GLYCOSAMINES, SELECTIVELY ACTIVE ON THE CANNABINOID PERIPHERAL RECEPTOR LIFEGROUP S.p.A. (IT) 1997-10-08 EP disclosed
WO-1996018600-A1 AMIDES OF MONO AND BICARBOXYLIC ACIDS WITH AMINO ACIDS OR GLYCOSAMINES, SELECTIVELY ACTIVE ON THE CANNABINOID PERIPHERAL RECEPTOR LIFEGROUP S.P.A. (IT) 1996-06-20 WO disclosed
US-5167709-A Improved spreadability KAO CORPORATION (JP) 1992-12-01 US disclosed
EP-0455018-A1 Pigment consisting of polyvalent metal salt of amidosulfonic acid and cosmetic composition containing the same KAO CORPORATION (JP) 1991-11-06 EP disclosed
US-4749515-A SULFOSUCCINIC ACID MONOESTERS, ACYLATED PEPTIDES; FOAMING, RINSING PROPERTIES LION CORPORATION (JP) 1988-06-07 US disclosed
US-4016287-A COSMETIC AND ANTIINFLAMMATORY BOEHRINGER INGELHEIM GMBH (DT) 1977-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160243014-A1 Optically Clear Acyl-Isethionate Aqueous Concentrate for Cosmetic Use ASNS, GATD3, IDUA FAAH 686/4885CNR1 3503/4885CNR2 2904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.