Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.76 |
| ▸ | CNR1 | P21554 | 2/20 | 0.76 |
| ▸ | CNR2 | P34972 | 2/20 | 0.76 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.68 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | CASP2 | P42575 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 4/20 | 0.61 |
| ▸ | PPARD | Q03181 | 4/20 | 0.61 |
| ▸ | PPARA | Q07869 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.61 |
| ▸ | TLR2 | O60603 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532448 | 1.00 | FAAH (0.76) | FAAHCNR1CNR2PLA2G2AEPHX2 | |
| SCHEMBL4000461 | 1.00 | FAAH (0.76) | FAAHCNR1CNR2PLA2G2AEPHX2 | |
| SCHEMBL531436 | 1.00 | FAAH (0.76) | FAAHCNR1CNR2PLA2G2AEPHX2 | |
| SCHEMBL9828949 | 1.00 | FAAH (0.76) | FAAHCNR1CNR2PLA2G2AEPHX2 | |
| SCHEMBL9193102 | 1.00 | FAAH (0.76) | FAAHCNR1CNR2PLA2G2AEPHX2 | |
| SCHEMBL9256918 | 1.00 | FAAH (0.76) | FAAHCNR1CNR2PLA2G2AEPHX2 | |
| SCHEMBL3990517 | 1.00 | FAAH (0.76) | FAAHCNR1CNR2PLA2G2AEPHX2 | |
| SCHEMBL5964111 | 1.00 | FAAH (0.76) | FAAHCNR1CNR2PLA2G2AEPHX2 | |
| SCHEMBL31529340 | 1.00 | FAAH (0.76) | FAAHCNR1CNR2PLA2G2AEPHX2 | |
| SCHEMBL688844 | 0.98 | FAAH (0.73) | FAAHCNR1CNR2PLA2G2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145944-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-05-05 | — | — | EP | disclosed |
| US-10392422-B2 | Macrocyclic broad spectrum antibiotics | RQX PHARMACEUTICALS, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-10351595-B2 | — | — | 2019-07-16 | — | — | US | disclosed |
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170088582-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. (US) | 2017-03-30 | — | — | US | disclosed |
| WO-2015179441-A2 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. (US) | 2015-11-26 | — | — | WO | disclosed |
| US-20150250882-A1 | Fatty Acid Acylated Amino Acids for Growth Hormone Delivery | NOVO NORDISK HEALTHCARE AG (CH) | 2015-09-10 | — | — | US | disclosed |
| EP-2908845-A1 | FATTY ACID ACYLATED AMINO ACIDS FOR GROWTH HORMONE DELIVERY | Novo Nordisk Health Care AG (CH) | 2015-08-26 | — | — | EP | disclosed |
| WO-2014060512-A1 | FATTY ACID ACYLATED AMINO ACIDS FOR GROWTH HORMONE DELIVERY | NOVO NORDISK HEALTH CARE AG (CH) | 2014-04-24 | — | — | WO | disclosed |
| US-6528068-B1 | An oily material for cosmetic compositions which oily material is an N-long-chain acyl neutral amino acid ester containing a straight-chain or branched-chain, saturated or unsaturated acyl group having from 6 to 22 carbon atoms, where the | AJINOMOTO CO., INC. (JP) | 2003-03-04 | — | — | US | disclosed |
| EP-0928608-A2 | Cosmetic composition | Ajinomoto Co., Inc. (JP) | 1999-07-14 | — | — | EP | disclosed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351595-B2 | — | MRPL21, PRSS1, PEPD | FAAH 2818/4885CNR1 4083/4885CNR2 4786/4885 |
| US-10392422-B2 | Macrocyclic broad spectrum antibiotics | MRPL21, PEPD, CTSC | FAAH 3193/4885CNR1 4151/4885CNR2 4813/4885 |
| US-20170088582-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | FAAH 3193/4885CNR1 4151/4885CNR2 4813/4885 |
| US-20150250882-A1 | Fatty Acid Acylated Amino Acids for Growth Hormone Delivery | GHRHR, GHSR, GHITM | FAAH 53/4885CNR1 3005/4885CNR2 2568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.