Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAN2A1 | Q16706 | 14/20 | 0.71 |
| ▸ | MAN1B1 | Q9UKM7 | 14/20 | 0.71 |
| ▸ | MAN2B1 | O00754 | 3/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4001130 | 1.00 | MAN2A1 (0.71) | MAN2A1MAN1B1MAN2B1GLANPC1 | |
| SCHEMBL2433156 | 0.74 | MAN1B1 (0.57) | MAN2A1MAN1B1MAN2B1GLA | |
| SCHEMBL27604321 | 0.70 | NPC1 (0.58) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3994042 | 0.70 | MAN1B1 (0.76) | MAN2A1MAN1B1MAN2B1 | |
| SCHEMBL8305696 | 0.66 | ALDH1A1 (0.66) | NPC1RAB9A | |
| SCHEMBL8305694 | 0.66 | ALDH1A1 (0.66) | NPC1RAB9A | |
| SCHEMBL31055430 | 0.65 | KMT2A (0.78) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL31055417 | 0.65 | L3MBTL1 (0.62) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29032735 | 0.64 | MEN1 (0.86) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL30450738 | 0.64 | MEN1 (0.86) | NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2067771-A1 | Derivatives of Dihydroxypyrrolidine as Anti-Cancer Compounds | EPFL Ecole Polytechnique Fédérale de Lausanne (CH) | 2009-06-10 | — | — | EP | disclosed |