Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.61 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 2/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17786381 | 0.81 | FYN (0.73) | ABCG2ABCB1MEN1KMT2AKDM4E | |
| SCHEMBL11672469 | 0.80 | ABCB1 (0.65) | CYP2C8PDE4AABCG2ABCB1MEN1 | |
| SCHEMBL7818265 | 0.79 | APP (0.74) | APPMAOBNPC1RAB9A | |
| SCHEMBL17667819 | 0.78 | CYP2C8 (0.55) | CYP2C8PDE4AABCG2ABCB1MEN1 | |
| SCHEMBL4002128 | 0.78 | CYP2C8 (0.76) | CYP2C8PDE4AABCG2ABCB1MEN1 | |
| SCHEMBL3010742 | 0.77 | CYP2C8 (0.74) | CYP2C8PDE4AABCG2ABCB1MEN1 | |
| SCHEMBL3013908 | 0.77 | CYP2C8 (0.86) | APPCYP2C8PDE4AABCG2ABCB1 | |
| SCHEMBL9947483 | 0.76 | MAOB (0.61) | APPKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL4005251 | 0.76 | GAPDH (0.55) | APPCYP2C8PDE4AABCG2ABCB1 | |
| SCHEMBL3008501 | 0.76 | CYP2C8 (0.59) | APPCYP2C8PDE4AABCG2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | disclosed |