Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4856143 | 0.80 | PARP1 (0.50) | PARP1LMNACES2CES1KIF11 | |
| SCHEMBL4005378 | 0.78 | KCNN4 (0.57) | MAPK1ALDH1A1MAPTHDAC3HDAC1 | |
| SCHEMBL1141842 | 0.78 | OGG1 (0.42) | CA1CA2HDAC3HDAC1HDAC2 | |
| SCHEMBL8447097 | 0.78 | MIF (0.44) | ALDH1A1LMNAMAPTHDAC3HDAC1 | |
| SCHEMBL431187 | 0.77 | HTT (0.59) | ALDH1A1LMNAMAPTHDAC1KIF11 | |
| SCHEMBL16892934 | 0.77 | CA1 (0.55) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL10813846 | 0.76 | CA1 (0.53) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL29756028 | 0.76 | MAPT (0.59) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL7039303 | 0.76 | CA1 (0.53) | CA1CA2PARP10PARP1PARP2 | |
| SCHEMBL30087732 | 0.74 | CA1 (0.52) | CA1CA2PARP10PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009079593-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |