Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 8/20 | 0.57 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002599 | 0.85 | HTT (0.58) | KCNN4KCNE1KCNQ1HTR7KDM4E | |
| SCHEMBL1141842 | 0.81 | OGG1 (0.42) | HDAC3HDAC1HDAC2HTTMEN1 | |
| SCHEMBL8447097 | 0.81 | MIF (0.44) | HPGDKDM4EHDAC3HDAC1HDAC2 | |
| SCHEMBL2171612 | 0.81 | KDM4E (0.44) | KCNN4HTR7HPGDKDM4EHDAC3 | |
| SCHEMBL431187 | 0.80 | HTT (0.59) | KCNN4KDM4EHDAC1HTTMAPT | |
| SCHEMBL8356496 | 0.79 | KCNN4 (0.55) | KCNN4KCNE1KCNQ1KDM4EHTT | |
| SCHEMBL4002525 | 0.78 | CA1 (0.49) | HDAC3HDAC1HDAC2MEN1NPC1 | |
| SCHEMBL16183044 | 0.76 | ESR1 (0.40) | HTTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11994187 | 0.74 | KCNN4 (0.53) | KCNN4KCNE1KCNQ1HTR7HPGD | |
| SCHEMBL11533320 | 0.74 | KCNN4 (0.45) | KCNN4KCNE1KCNQ1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009079593-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |