Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 8/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3996737 | 0.81 | CHRNB2 (0.46) | SLC6A2SSTR4SLC6A4 | |
| SCHEMBL3996423 | 0.79 | SSTR4 (0.39) | SSTR4CD274 | |
| SCHEMBL4002672 | 0.79 | SSTR4 (0.41) | SLC6A2SSTR4SLC6A4 | |
| SCHEMBL8292968 | 0.74 | SSTR4 (0.45) | SLC6A2SSTR4SLC6A4 | |
| SCHEMBL3742282 | 0.74 | SSTR4 (0.45) | SLC6A2SSTR4SLC6A4 | |
| Hydrochloric Acid SCHEMBL4031709 | 0.73 | SSTR4 (0.44) | SLC6A2SSTR4SLC6A4 | |
| Hydrochloric Acid SCHEMBL27204360 | 0.71 | SSTR4 (0.42) | SSTR4 | |
| Hydrochloric Acid SCHEMBL27164880 | 0.71 | SSTR4 (0.42) | SSTR4 | |
| SCHEMBL25214712 | 0.71 | SSTR4 (0.43) | SLC6A2SSTR4SLC6A4 | |
| SCHEMBL1927711 | 0.69 | FOLH1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071895-A1 | FUSED THIAZOLE AND THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | disclosed |