SCHEMBL4002672

SCHEMBL4002672

O=C(c1ccccc1-c1ccccc1F)C1CNCCO1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 14/20 0.41
NPC1 O15118 2/20 0.38
POLB P06746 2/20 0.38
RAB9A P51151 2/20 0.38
ALDH1A1 P00352 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
REN P00797 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3996737 0.84 CHRNB2 (0.46) SSTR4ALDH1A1SMN1; SMN2SLC6A2SLC6A4
SCHEMBL7753826 0.79 SSTR4 (0.43) SSTR4ALDH1A1SMN1; SMN2SLC6A2SLC6A4
SCHEMBL25214712 0.79 SSTR4 (0.43) SSTR4ALDH1A1SLC6A2SLC6A4REN
SCHEMBL4002679 0.79 SLC6A2 (0.43) SSTR4SLC6A2SLC6A4
SCHEMBL8543691 0.78 SSTR4 (0.42) SSTR4SLC6A2SLC6A4REN
SCHEMBL6938281 0.78 GAA (0.45) SSTR4SLC6A2SLC6A4
SCHEMBL11446441 0.78 SSTR4 (0.42) SSTR4SLC6A2SLC6A4REN
SCHEMBL1586743 0.77 SSTR4 (0.39) SSTR4SLC6A2SLC6A4REN
SCHEMBL3766721 0.77 SSTR4 (0.38) SSTR4SLC6A2SLC6A4REN
Hydrochloric Acid SCHEMBL27164880 0.77 SSTR4 (0.42) SSTR4NPC1POLBRAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009071895-A1 FUSED THIAZOLE AND THIOPHENE DERIVATIVES AS KINASE INHIBITORS UCB PHARMA S.A. (BE) 2009-06-11 WO disclosed