Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | ME3 | Q16798 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4153054 | 1.00 | CNR1 (0.43) | CNR1ALDH1A1MCHR1LMNASMN1; SMN2 | |
| SCHEMBL4010313 | 0.91 | CNR1 (0.47) | CNR1ALDH1A1LMNAEPHX2DRD2 | |
| SCHEMBL4011966 | 0.90 | ALDH1A1 (0.46) | CNR1ALDH1A1LMNAHRH3GAA | |
| SCHEMBL5950713 | 0.90 | ALDH1A1 (0.46) | CNR1ALDH1A1LMNAHRH3GAA | |
| SCHEMBL28769935 | 0.88 | CNR1 (0.43) | CNR1ALDH1A1LMNASMN1; SMN2HRH3 | |
| SCHEMBL4005560 | 0.85 | CNR1 (0.38) | CNR1ALDH1A1DRD2DRD3KMT2A | |
| SCHEMBL5950362 | 0.85 | CNR1 (0.38) | CNR1ALDH1A1DRD2DRD3KMT2A | |
| SCHEMBL4148781 | 0.85 | CNR1 (0.48) | CNR1ALDH1A1LMNASMN1; SMN2DRD2 | |
| SCHEMBL27707859 | 0.84 | CNR1 (0.38) | CNR1ALDH1A1DRD2DRD3GAA | |
| SCHEMBL4140568 | 0.83 | EPHX1 (0.43) | KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | claimed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | claimed |