Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5950713 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL4010313 | 0.91 | CNR1 (0.47) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL28769935 | 0.91 | CNR1 (0.43) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL4002885 | 0.90 | CNR1 (0.43) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL4153054 | 0.90 | CNR1 (0.43) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL5950232 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL4006388 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL4005560 | 0.86 | CNR1 (0.38) | ALDH1A1KMT2AMAPTCNR1EPHX1 | |
| SCHEMBL5950362 | 0.86 | CNR1 (0.38) | ALDH1A1KMT2AMAPTCNR1EPHX1 | |
| SCHEMBL5950384 | 0.86 | SYK (0.40) | ALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |