Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4003868 | 1.00 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL4003844 | 0.83 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL4000400 | 0.81 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL4004071 | 0.79 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL5802846 | 0.79 | HCRTR1 (0.64) | HCRTR1HCRTR2 | |
| SCHEMBL1398620 | 0.76 | HCRTR1 (0.90) | HCRTR1HCRTR2 | |
| SCHEMBL1398707 | 0.76 | HCRTR1 (0.90) | HCRTR1HCRTR2 | |
| SCHEMBL1398677 | 0.76 | HCRTR1 (0.90) | HCRTR1HCRTR2 | |
| SCHEMBL269854 | 0.76 | HCRTR1 (0.66) | HCRTR1HCRTR2 | |
| SCHEMBL271167 | 0.76 | HCRTR1 (0.66) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069332-A2 | AZETIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008020405-A2 | AZETIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-02-21 | — | — | WO | disclosed |