Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 7/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1239528 | 0.88 | CCR9 (0.38) | CCR9NR1H4PTGESALOX5ESRRG | |
| SCHEMBL4008718 | 0.84 | PTPN1 (0.43) | CCR9SERPINE1NR1H4PTGESALOX5 | |
| SCHEMBL4010103 | 0.81 | SERPINE1 (0.48) | SERPINE1NR1H4PTGESALOX5HDAC6 | |
| SCHEMBL1241613 | 0.80 | SERPINE1 (0.49) | SERPINE1NR1H4 | |
| SCHEMBL1241573 | 0.80 | SERPINE1 (0.57) | SERPINE1NR1H4PTGESALOX5 | |
| SCHEMBL4006485 | 0.80 | SERPINE1 (0.45) | SERPINE1NR1H4PTGESALOX5HDAC6 | |
| SCHEMBL4441053 | 0.78 | NR1H4 (0.52) | CCR9SERPINE1NR1H4PTGESALOX5 | |
| SCHEMBL4005059 | 0.77 | NR1H4 (0.43) | CCR9SERPINE1NR1H4PTGESALOX5 | |
| SCHEMBL1242713 | 0.75 | SERPINE1 (0.58) | SERPINE1NR1H4PTGESALOX5 | |
| SCHEMBL1241447 | 0.73 | PTPN1 (0.41) | CCR9NR1H4HDAC6HDAC8HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072498-A1 | N-PHENYLOXAMIDIC ACID DERIVATIVE | Institute of Medicinal Molecular Design, Inc. (JP) | 2009-06-24 | — | — | EP | disclosed |