Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CCR9 | P51686 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 8/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 2/20 | 0.39 |
| ▸ | GIPR | P48546 | 2/20 | 0.39 |
| ▸ | GLP1R | P43220 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241447 | 0.90 | PTPN1 (0.41) | PTPN1CCR9PTGER1GCGRGIPR | |
| SCHEMBL1241436 | 0.85 | SERPINE1 (0.56) | SERPINE1GCGRGIPRGLP1RNR1H4 | |
| SCHEMBL4003060 | 0.84 | CCR9 (0.42) | CCR9SERPINE1NR1H4PTGESALOX5 | |
| SCHEMBL14635713 | 0.79 | SERPINE1 (0.44) | PTPN1SERPINE1PTGER1HRH4HIF1A | |
| SCHEMBL1241445 | 0.79 | SERPINE1 (0.52) | PTPN1SERPINE1GCGRGIPRGLP1R | |
| SCHEMBL1239797 | 0.78 | SERPINE1 (0.46) | SERPINE1GCGRGIPRGLP1RNR1H4 | |
| SCHEMBL1242219 | 0.77 | SERPINE1 (0.54) | SERPINE1GCGRGIPRGLP1RNR1H4 | |
| SCHEMBL1239503 | 0.76 | SERPINE1 (0.56) | SERPINE1GCGRGIPRGLP1RNR1H4 | |
| SCHEMBL1241573 | 0.76 | SERPINE1 (0.57) | SERPINE1GCGRGIPRGLP1RNR1H4 | |
| SCHEMBL1241454 | 0.76 | SERPINE1 (0.55) | SERPINE1GCGRGIPRGLP1RNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072498-A1 | N-PHENYLOXAMIDIC ACID DERIVATIVE | Institute of Medicinal Molecular Design, Inc. (JP) | 2009-06-24 | — | — | EP | disclosed |