Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | CCR9 | P51686 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1239513 | 0.86 | MMP9 (0.41) | NR1H4PTGESALOX5MMP9MMP13 | |
| SCHEMBL4441053 | 0.82 | NR1H4 (0.52) | NR1H4PTGESALOX5CCR9ALDH1A1 | |
| SCHEMBL4010103 | 0.80 | SERPINE1 (0.48) | NR1H4PTGESALOX5HDAC8HDAC6 | |
| SCHEMBL1241546 | 0.78 | SERPINE1 (0.58) | NR1H4PTGESALOX5SERPINE1EPHX2 | |
| SCHEMBL4003060 | 0.77 | CCR9 (0.42) | NR1H4PTGESALOX5CCR9HDAC8 | |
| SCHEMBL1241458 | 0.76 | PTGES (0.63) | NR1H4PTGESALOX5SERPINE1 | |
| SCHEMBL1241427 | 0.75 | PTGES (0.53) | NR1H4PTGESALOX5HDAC3MEN1 | |
| SCHEMBL1241489 | 0.75 | PTGES (0.58) | NR1H4PTGESALOX5RAB9ASERPINE1 | |
| SCHEMBL1241456 | 0.74 | CCR9 (0.39) | NR1H4PTGESALOX5CCR9MMP9 | |
| SCHEMBL4006485 | 0.74 | SERPINE1 (0.45) | NR1H4PTGESALOX5HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072498-A1 | N-PHENYLOXAMIDIC ACID DERIVATIVE | Institute of Medicinal Molecular Design, Inc. (JP) | 2009-06-24 | — | — | EP | disclosed |