Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387512 | 1.00 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL1405817 | 0.84 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL9615934 | 0.84 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL1405818 | 0.84 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL5907164 | 0.84 | ALDH1A1 (0.45) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL6278540 | 0.84 | ALDH1A1 (0.45) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8057318 | 0.83 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL27730076 | 0.83 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL27807523 | 0.83 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL16230542 | 0.83 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409164-B1 | Phenacylpyridiniothiocephalosporins | SHIONOGI & CO (JP) | 1996-06-05 | — | — | EP | claimed |
| US-5134138-A | ANTIBIOTICS | SHIONOGI & CO., LTD. (JP) | 1992-07-28 | — | — | US | claimed |
| EP-0409164-A2 | Phenacylpyridiniothiocephalosporins | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-01-23 | — | — | EP | claimed |
| US-4978613-A | Beta-lactamase assay employing chromogenic precipitating substrates | ABBOTT LABORATORIES (US) | 1990-12-18 | — | — | US | claimed |
| US-7511135-B2 | Method for manufacture of ceftiofur | LUPIN LIMITED (IN) | 2009-03-31 | — | — | US | disclosed |
| US-7470786-B2 | Method for manufacture of ceftriaxone sodium | LUPIN LIMITED (IN) | 2008-12-30 | — | — | US | disclosed |
| US-20080207912-A1 | Method for manufacture of ceftiofur | LUPIN LIMITED | 2008-08-28 | — | — | US | disclosed |
| US-20080200670-A1 | METHOD FOR THE MANUFACTURE OF CEFTRIAXONE SODIUM | LUPIN LIMITED (RESEARCH PARK) (IN) | 2008-08-21 | — | — | US | disclosed |
| EP-1556388-B1 | A METHOD FOR MANUFACTURE OF CEFTIOFUR | LUPIN LTD (IN) | 2007-09-19 | — | — | EP | disclosed |
| US-20070049749-A1 | Method for Manufacture of Ceftriaxone Sodium | LUPIN LIMITED (RESEARCH PARK) (IN) | 2007-03-01 | — | — | US | disclosed |
| US-20070015917-A1 | Method For Manufacture of Ceftriaxone Sodium | LUPIN LIMITED (RESEARCH PARK) (IN) | 2007-01-18 | — | — | US | disclosed |
| US-20060149054-A1 | Method for manufacture of ceftiofur | LUPIN LIMITED (IN) | 2006-07-06 | — | — | US | disclosed |
| US-4837318-A | Carbonate substituted monobactams as antibiotics | THE UPJOHN COMPANY (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0271829-A2 | Delta-hydroxy-beta-lysine derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1988-06-22 | — | — | EP | disclosed |
| EP-0249909-A1 | Tricyclic penam compounds, their production and their use | Takeda Chemical Industries, Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |
| EP-0250096-A1 | Isoxazolone derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |
| EP-0219923-A1 | Antibiotic derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-04-29 | — | — | EP | disclosed |
| EP-0191989-A1 | Antibiotic isoxazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |
| EP-0002605-B1 | CEPHALOSPORIN COMPOUNDS AND FORMULATIONS CONTAINING THEM FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS AND THE PREPARATION OF THE CEPHALOSPORIN COMPOUNDS | ELI LILLY AND COMPANY (US) | 1981-12-30 | — | — | EP | disclosed |
| US-4200745-A | 7[2-(2-Aminothiazol-4-yl)-2-alkoxyimino]acetamido 3[4-alkyl-5-oxo-6-hydroxy-3,4 dihydro 1,2,4-triazin 3-yl]thio methyl cephalosporins | ELI LILLY AND COMPANY (US) | 1980-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207912-A1 | Method for manufacture of ceftiofur | APEH, COASY, PCMT1 | MAPT 864/4885ALDH1A1 475/4885MEN1 2882/4885 |
| US-20060149054-A1 | Method for manufacture of ceftiofur | APEH, COASY, PCMT1 | MAPT 806/4885ALDH1A1 615/4885MEN1 3040/4885 |
| US-20070049749-A1 | Method for Manufacture of Ceftriaxone Sodium | TREH, CHAT, MRPL21 | MAPT 1150/4885ALDH1A1 1915/4885MEN1 1624/4885 |
| US-20070015917-A1 | Method For Manufacture of Ceftriaxone Sodium | TREH, CHAT, MRPL21 | MAPT 1150/4885ALDH1A1 1915/4885MEN1 1624/4885 |
| US-20080200670-A1 | METHOD FOR THE MANUFACTURE OF CEFTRIAXONE SODIUM | CHAT, TREH, MRPL21 | MAPT 949/4885ALDH1A1 1869/4885MEN1 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.