Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.46 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4000515 | 0.96 | KMT2A (0.53) | KMT2AMEN1ALDH1A1SMN1; SMN2NR2F2 | |
| SCHEMBL3997265 | 0.91 | KMT2A (0.54) | KMT2AMEN1ALDH1A1SMN1; SMN2NR2F2 | |
| SCHEMBL3999131 | 0.83 | KMT2A (0.82) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL3995363 | 0.81 | BRD4 (0.55) | ALDH1A1CNR2 | |
| SCHEMBL3997147 | 0.81 | RORC (0.48) | KMT2AMEN1ALDH1A1CNR2 | |
| SCHEMBL3998713 | 0.80 | KMT2A (0.77) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL3999074 | 0.77 | KMT2A (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL4967041 | 0.77 | KDM4E (0.57) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4967937 | 0.76 | HPGD (0.57) | KMT2AMEN1ALDH1A1MAPTHCAR3 | |
| SCHEMBL1962657 | 0.74 | KCNH3 (0.55) | KMT2AALDH1A1SMN1; SMN2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598393-B2 | Sulfonyl benzimidazole derivatives | PFIZER INC. (US) | 2009-10-06 | — | — | US | disclosed |
| EP-1809607-B1 | SULFONYL BENZIMIDAZOLE DERIVATIVES | PFIZER (US) | 2008-12-17 | — | — | EP | disclosed |
| US-20060094750-A1 | Sulfonyl benzimidazole derivatives | KON-I KANA | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094750-A1 | Sulfonyl benzimidazole derivatives | TRPV1, CNR2, CNR1 | KMT2A 4021/4885MEN1 3669/4885ALDH1A1 2810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.