Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 7/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2701835 | 0.82 | MAOA (0.61) | SLC6A9MAOAMAOBTAAR1DPP4 | |
| SCHEMBL8279640 | 0.81 | SLC6A9 (0.66) | SLC6A9KDM4EHSD17B10 | |
| SCHEMBL2701661 | 0.79 | MAOA (0.53) | SLC6A9MAOAMAOBTAAR1DPP4 | |
| SCHEMBL2702188 | 0.79 | MAOA (0.53) | SLC6A9MAOAMAOBTAAR1GAA | |
| SCHEMBL5585246 | 0.78 | SLC6A9 (0.57) | SLC6A9GAAPKMMAPTPOLB | |
| SCHEMBL2701656 | 0.78 | GAA (0.53) | SLC6A9GAAPKMMAPTPOLB | |
| SCHEMBL14538120 | 0.78 | SLC6A9 (0.57) | SLC6A9GAAPKMMAPTPOLB | |
| SCHEMBL5584985 | 0.78 | SLC6A9 (0.67) | SLC6A9 | |
| SCHEMBL5584907 | 0.78 | SLC6A9 (0.74) | SLC6A9LMNA | |
| SCHEMBL3560433 | 0.77 | SLC6A9 (0.65) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1684759-A4 | 4-PHENYL PIPERDINE SULFONYL GLYCINE TRANSPORTER INHIBITORS | MERCK & CO INC (US) | 2009-06-10 | — | — | EP | disclosed |
| US-20070105902-A1 | 4-Phenyl piperdine sulfonyl glycine transporter inhibitors | MERCK SHARP & DOHME CORP. | 2007-05-10 | — | — | US | disclosed |
| US-20070105902-A1 | 4-Phenyl piperdine sulfonyl glycine transporter inhibitors | MERCK SHARP & DOHME CORP. | 2007-05-10 | — | — | US | disclosed |
| US-20070105902-A1 | 4-Phenyl piperdine sulfonyl glycine transporter inhibitors | MERCK SHARP & DOHME CORP. | 2007-05-10 | — | — | US | disclosed |
| EP-1684759-A2 | 4-PHENYL PIPERDINE SULFONYL GLYCINE TRANSPORTER INHIBITORS | Merck & Co., Inc. (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005046601-A2 | 4-PHENYL PIPERDINE SULFONYL GLYCINE TRANSPORTER INHIBITORS | MERCK & CO., INC. (US) | 2005-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105902-A1 | 4-Phenyl piperdine sulfonyl glycine transporter inhibitors | SLC1A2, SLC1A1, SLC1A3 | SLC6A9 10/4885MAOA 1935/4885MAOB 1440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.