SCHEMBL4003501

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4005427	0.88	DRD4 (0.78)	ALDH1A1DRD4DRD2DRD3LMNA
	SCHEMBL4002606	0.87	DRD4 (0.76)	ALDH1A1DRD4DRD2DRD3KMT2A
	SCHEMBL4004877	0.87	DRD4 (0.76)	ALDH1A1DRD4DRD2DRD3KMT2A
	SCHEMBL4008994	0.86	DRD4 (0.74)	ALDH1A1DRD4DRD2DRD3KMT2A
	SCHEMBL4004396	0.84	DRD4 (0.72)	ALDH1A1DRD4DRD2DRD3KMT2A
	SCHEMBL4010603	0.84	DRD4 (1.00)	ALDH1A1DRD4DRD2DRD3CYP1A2
	SCHEMBL4005507	0.84	DRD4 (1.00)	ALDH1A1TSHRDRD4DRD2DRD3
	SCHEMBL4009628	0.84	DRD4 (0.70)	ALDH1A1DRD4DRD2DRD3SMN1; SMN2
	SCHEMBL4010981	0.83	MEN1 (0.81)	ALDH1A1DRD4DRD2DRD3SMN1; SMN2
	SCHEMBL4004333	0.83	DRD4 (0.81)	ALDH1A1TSHRDRD4DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.