Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4003524 | 1.00 | CNR1 (0.49) | CNR1USP30ALDH1A1DRD2DRD3 | |
| SCHEMBL612468 | 0.87 | ALDH1A1 (0.52) | CNR1USP30ALDH1A1DRD2DRD3 | |
| SCHEMBL4144804 | 0.84 | EPHX2 (0.47) | SLC5A1EPHX2NOTUM | |
| SCHEMBL4005564 | 0.83 | CNR1 (0.52) | CNR1USP30ALDH1A1DRD2DRD3 | |
| SCHEMBL4005571 | 0.83 | CNR1 (0.52) | CNR1USP30ALDH1A1DRD2DRD3 | |
| SCHEMBL4006089 | 0.82 | DRD2 (0.61) | CNR1USP30ALDH1A1DRD2DRD3 | |
| SCHEMBL4007370 | 0.82 | DRD2 (0.61) | CNR1USP30ALDH1A1DRD2DRD3 | |
| SCHEMBL4006081 | 0.82 | DRD2 (0.61) | CNR1USP30ALDH1A1DRD2DRD3 | |
| SCHEMBL4148809 | 0.82 | DRD2 (0.61) | CNR1USP30ALDH1A1DRD2DRD3 | |
| SCHEMBL4552162 | 0.80 | CNR1 (0.56) | CNR1USP30ALDH1A1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |