Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4003906 | 1.00 | PKM (0.49) | PKMATMALDH1A1MAPTKMT2A | |
| SCHEMBL12120933 | 0.84 | ATM (0.67) | PKMATMALDH1A1MAPTKMT2A | |
| SCHEMBL1419333 | 0.82 | ATM (0.69) | PKMATMALDH1A1MAPTKMT2A | |
| SCHEMBL4004085 | 0.81 | ATM (0.45) | PKMATMALDH1A1MAPTKMT2A | |
| SCHEMBL4004092 | 0.81 | ATM (0.45) | PKMATMALDH1A1MAPTKMT2A | |
| SCHEMBL1233089 | 0.78 | PKM (0.47) | PKMATMALDH1A1MAPTKMT2A | |
| SCHEMBL1233090 | 0.78 | PKM (0.47) | PKMATMALDH1A1MAPTKMT2A | |
| SCHEMBL9904825 | 0.76 | MAPT (0.68) | PKMATMALDH1A1MAPTKMT2A | |
| SCHEMBL9904823 | 0.76 | MAPT (0.68) | PKMATMALDH1A1MAPTKMT2A | |
| SCHEMBL12123691 | 0.75 | GRIN2D (0.47) | PKMALDH1A1MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009074157-A1 | FULLY-MODIFIED PHENYL PYRROLE AMINOGUANIDINES | ACTION PHARMA A/S (DK) | 2009-06-18 | — | — | WO | disclosed |