Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4004092 | 1.00 | ATM (0.45) | ATMALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4001880 | 0.83 | ATM (0.65) | ATMALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL12120933 | 0.82 | ATM (0.67) | ATMALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4003906 | 0.81 | PKM (0.49) | ATMALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4003909 | 0.81 | PKM (0.49) | ATMALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL17537305 | 0.73 | ALDH1A1 (0.35) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1224353 | 0.70 | CYP1A2 (0.57) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL1922783 | 0.70 | CYP1A2 (0.57) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL25286936 | 0.69 | ATM (0.62) | ATMALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL28817910 | 0.69 | ALDH1A1 (0.49) | ATMALDH1A1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009074157-A1 | FULLY-MODIFIED PHENYL PYRROLE AMINOGUANIDINES | ACTION PHARMA A/S (DK) | 2009-06-18 | — | — | WO | disclosed |