Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7550214 | 0.95 | HDAC3 (0.44) | NAAAHDAC3HDAC1HDAC2NPC1 | |
| SCHEMBL7554228 | 0.89 | KMT2A (0.42) | NAAAHDAC3HDAC1HDAC2NPC1 | |
| SCHEMBL11325678 | 0.87 | HSD17B3 (0.49) | HDAC3HDAC1HDAC2MAPTHSD17B3 | |
| SCHEMBL11679790 | 0.87 | HSD17B3 (0.49) | HDAC3HDAC1HDAC2MAPTHSD17B3 | |
| SCHEMBL11324137 | 0.87 | HSD17B3 (0.49) | HDAC3HDAC1HDAC2MAPTHSD17B3 | |
| SCHEMBL11313632 | 0.87 | HSD17B3 (0.49) | HDAC3HDAC1HDAC2MAPTHSD17B3 | |
| SCHEMBL11318345 | 0.87 | HSD17B3 (0.49) | HDAC3HDAC1HDAC2MAPTHSD17B3 | |
| SCHEMBL11325230 | 0.84 | HDAC3 (0.47) | HDAC3HDAC1HDAC2HPGDGAA | |
| SCHEMBL3125344 | 0.83 | CES2 (0.55) | NAAANPC1LMNAHPGDMAPT | |
| SCHEMBL7554003 | 0.82 | KMT2A (0.45) | NAAAHDAC3HDAC1HDAC2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2068873-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | Pharma 2100 (DK) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008031440-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | PHARMA 2100 (DK) | 2008-03-20 | — | — | WO | disclosed |