Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7865524 | 0.99 | MAPT (0.52) | MAPTCYP1A2CYP2C9ALDH1A1GAA | |
| SCHEMBL7325158 | 0.88 | PRSS1 (0.56) | MAPTALDH1A1GAALMNAKMT2A | |
| Guanidine SCHEMBL1486812 | 0.84 | MAPT (0.68) | MAPTCYP1A2CYP2C9ALDH1A1GAA | |
| SCHEMBL7331050 | 0.83 | PRSS1 (0.51) | MAPTALDH1A1GAALMNAKMT2A | |
| SCHEMBL7329499 | 0.82 | KMT2A (0.56) | MAPTCYP1A2CYP2C9ALDH1A1GAA | |
| SCHEMBL4071946 | 0.81 | MAPT (0.60) | MAPTCYP1A2CYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL3150116 | 0.81 | MAPT (0.63) | MAPTCYP1A2CYP2C9ALDH1A1LMNA | |
| SCHEMBL527543 | 0.80 | MAPT (0.71) | MAPTCYP1A2CYP2C9ALDH1A1GAA | |
| SCHEMBL30727558 | 0.80 | MAPT (0.71) | MAPTCYP1A2CYP2C9ALDH1A1GAA | |
| SCHEMBL5078869 | 0.80 | ALDH1A1 (0.56) | MAPTCYP1A2CYP2C9ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170315114-A1 | BIMOLECULAR AUTOINHIBITED BIOSENSOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-11-02 | — | — | US | disclosed |
| US-9791436-B2 | Protease-based biosensor | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-10-17 | — | — | US | disclosed |
| US-9772328-B2 | Bimolecular protease-based biosensor | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-09-26 | — | — | US | disclosed |
| EP-3213073-A1 | BIMOLECULAR AUTOINHIBITED BIOSENSOR | The University Of Queensland (AU) | 2017-09-06 | — | — | EP | disclosed |
| EP-2895859-B1 | PROTEASE-BASED BIOSENSOR MOLECULE | UNIV QUEENSLAND (AU) | 2017-05-17 | — | — | EP | disclosed |
| US-20160223529-A1 | BIMOLECULAR PROTEASE-BASED BIOSENSOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2016-08-04 | — | — | US | disclosed |
| WO-2016065415-A1 | BIMOLECULAR AUTOINHIBITED BIOSENSOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2016-05-06 | — | — | WO | disclosed |
| US-20150226731-A1 | PROTEASE-BASED BIOSENSOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2015-08-13 | — | — | US | disclosed |
| EP-2895859-A1 | PROTEASE-BASED BIOSENSOR | The University of Queensland (AU) | 2015-07-22 | — | — | EP | disclosed |
| WO-2014040129-A1 | PROTEASE-BASED BIOSENSOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2014-03-20 | — | — | WO | disclosed |
| WO-2003070746-A2 | PURIFICATION AND CHARACTERIZATION OF A PROTHROMBIN ACTIVATOR FROM THE BRISTLED OF LONOMIA OBLIQUA | BIOLAB SANUS FARMACÊUTICA LTDA. (BR) | 2003-08-28 | — | — | WO | disclosed |
| EP-1242607-A1 | TRANSGENIC INSECT | Implyx Ltd. (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001044483-A1 | TRANSGENIC INSECT | IMPLYX LTD. (GB) | 2001-06-21 | — | — | WO | disclosed |
| EP-0891426-A2 | HUMAN BIKUNIN | Bayer Corporation (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997033996-A2 | HUMAN BIKUNIN | BAYER CORPORATION (US) | 1997-09-18 | — | — | WO | disclosed |
| EP-0602101-A1 | INJECTION/ACTIVATION APPARATUS | ORION THERAPEUTIC SYSTEMS, INC. (US) | 1994-06-22 | — | — | EP | disclosed |
| WO-1993004729-A1 | INJECTION/ACTIVATION APPARATUS | ORION THERAPEUTIC SYSTEMS, INC. (US) | 1993-03-18 | — | — | WO | disclosed |
| EP-0380084-A2 | Method for the inhibition of cell-cell and cell substratum interactions by the blocking of carbohydrate-carbohydrate interactions | The Biomembrane Institute (US) | 1990-08-01 | — | — | EP | disclosed |
| US-4150049-A | P-NITROPHENYL AMIDINOPHENYLMETHANESULFONATE, THROMBIN INACTIVATION | THE GOVERNMENT OF THE UNITED STATES (US) | 1979-04-17 | — | — | US | disclosed |
| US-4001087-A | INACTIVATION OF THROMBIN | THE UNITED STATES OF AMERICA (US) | 1977-01-04 | — | — | US | disclosed |