Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | MAX | P61244 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11307087 | 0.81 | KDM4E (0.55) | ALDH1A1MAPTCYP1A2CYP2C9KMT2A | |
| SCHEMBL4451329 | 0.81 | KMT2A (0.50) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL6888440 | 0.80 | KMT2A (0.49) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL4005710 | 0.80 | MAPT (0.53) | ALDH1A1MAPTCYP1A2CYP2C9KMT2A | |
| SCHEMBL4905868 | 0.79 | KMT2A (0.62) | ALDH1A1MAPTCYP2C9KCNMA1KMT2A | |
| Hydrochloric Acid SCHEMBL7865524 | 0.79 | MAPT (0.52) | ALDH1A1MAPTCYP1A2CYP2C9KMT2A | |
| Bicarbonate SCHEMBL9506388 | 0.78 | KMT2A (0.61) | ALDH1A1MAPTCYP2C9KCNMA1KMT2A | |
| Hydrochloric Acid SCHEMBL15527205 | 0.77 | KMT2A (0.60) | ALDH1A1MAPTCYP2C9KCNMA1KMT2A | |
| SCHEMBL10782877 | 0.76 | ALDH1A1 (0.59) | ALDH1A1MAPTCYP1A2CYP2C9KCNMA1 | |
| SCHEMBL10677499 | 0.76 | HPGD (0.51) | ALDH1A1MAPTCYP1A2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4654298-A | Method for detection of peritoneal inflammation or infection | ABBOTT LABORATORIES (US) | 1987-03-31 | — | — | US | claimed |
| EP-0178501-A1 | Method for detection of peritoneal inflammation or infection | ABBOTT LABORATORIES (US) | 1986-04-23 | — | — | EP | claimed |
| EP-1976861-A2 | INHIBITING TUMOUR CELL INVASION, METASTASIS AND ANGIOGENESIS THROUGH TARGETTING LEGUMAIN | The Scripps Research Institute (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007064759-A2 | INHIBITING TUMOUR CELL INVASION, METASTASIS AND ANGIOGENESIS THROUGH TARGETTING LEGUMAIN | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-06-07 | — | — | WO | disclosed |
| EP-0892849-A4 | METHODS FOR USING THE OBESE GENE AND ITS GENE PRODUCT TO STIMULATE HEMATOPOIETIC DEVELOPMENT | PROGENITOR INC (US) | 2004-08-25 | — | — | EP | disclosed |
| EP-0892849-A1 | METHODS FOR USING THE OBESE GENE AND ITS GENE PRODUCT TO STIMULATE HEMATOPOIETIC DEVELOPMENT | Progenitor, Inc. (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997027286-A9 | METHODS FOR USING THE OBESE GENE AND ITS GENE PRODUCT TO STIMULATE HEMATOPOIETIC DEVELOPMENT | — | 1997-11-20 | — | — | WO | disclosed |
| WO-1997027286-A1 | METHODS FOR USING THE OBESE GENE AND ITS GENE PRODUCT TO STIMULATE HEMATOPOIETIC DEVELOPMENT | PROGENITOR, INC. (US) | 1997-07-31 | — | — | WO | disclosed |
| US-5147790-A | Tissue plasminogen activator, biosynthesis | T-PA TECHNOLOGY TRUST | 1992-09-15 | — | — | US | disclosed |
| EP-0113319-B1 | CELL LINES AND THEIR USE FOR THE PRODUCTION OF PROTEINS | Wilson, Elaine Lynette, Dr. (ZA) | 1991-08-28 | — | — | EP | disclosed |
| EP-0178501-B1 | METHOD FOR DETECTION OF PERITONEAL INFLAMMATION OR INFECTION | ABBOTT LABORATORIES (US) | 1989-11-08 | — | — | EP | disclosed |
| EP-0143081-B1 | SYNTHESIS OF TISSUE PLASMINOGEN ACTIVATOR(TPA) BY YEAST | CIBA-GEIGY AG (CH) | 1989-08-23 | — | — | EP | disclosed |
| US-4798796-A | Cell lines and their use for the production plasminogen activators | BIO-RESPONSE, INC. (US) | 1989-01-17 | — | — | US | disclosed |
| US-4717652-A | LEUKOCYTE LYSING AGENT AND CHROMOGENIC OR FLUOROGENIC ENZYME SUBSTRATE | ABBOTT LABORATORIES (US) | 1988-01-05 | — | — | US | disclosed |
| US-4693970-A | Immunoassay using complement | BECTON, DICKINSON AND COMPANY (US) | 1987-09-15 | — | — | US | disclosed |
| US-4654298-A | Method for detection of peritoneal inflammation or infection | ABBOTT LABORATORIES (US) | 1987-03-31 | — | — | US | disclosed |
| EP-0178501-A1 | Method for detection of peritoneal inflammation or infection | ABBOTT LABORATORIES (US) | 1986-04-23 | — | — | EP | disclosed |
| EP-0143081-A2 | Synthesis of tissue plasminogen activator(TPA) by yeast | CIBA-GEIGY AG (CH) | 1985-05-29 | — | — | EP | disclosed |
| EP-0113319-A2 | Cell lines and their use for the production of proteins | Wilson, Elaine Lynette, Dr. (ZA) | 1984-07-11 | — | — | EP | disclosed |