Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Acetylthiocholine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 5/20 | 0.41 |
| ▸ | CHRM1 known ✓ | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 known ✓ | P20309 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.95 |
| ▸ | BLM | P54132 | 2/20 | 0.91 |
| ▸ | POLB | P06746 | 1/20 | 0.91 |
| ▸ | ATM | Q13315 | 1/20 | 0.91 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetylthiocholine SCHEMBL77666 | 0.97 | CYP2C19 (1.00) | CYP2C19BLMPOLBATMACHE | |
| Acetylthiocholine SCHEMBL16322376 | 0.95 | CYP2C19 (0.95) | CYP2C19BLMPOLBATMACHE | |
| Acetylthiocholine SCHEMBL1276372 | 0.95 | BLM (1.00) | CYP2C19BLMPOLBATMACHE | |
| Acetylthiocholine SCHEMBL4318618 | 0.95 | CYP2C19 (0.95) | CYP2C19BLMPOLBATMACHE | |
| Acetylthiocholine SCHEMBL27356791 | 0.95 | CYP2C19 (0.95) | CYP2C19BLMPOLBATMACHE | |
| Acetylthiocholine SCHEMBL7172548 | 0.95 | CYP2C19 (0.95) | CYP2C19BLMPOLBATMACHE | |
| Acetylthiocholine SCHEMBL4318613 | 0.95 | CYP2C19 (0.95) | CYP2C19BLMPOLBATMACHE | |
| Acetylthiocholine SCHEMBL28172987 | 0.89 | CYP2C19 (0.76) | CYP2C19BLMPOLBATMACHE | |
| Acetylthiocholine SCHEMBL3720144 | 0.89 | CYP2C19 (0.76) | CYP2C19BLMPOLBATMACHE | |
| Acetylthiocholine SCHEMBL9097185 | 0.89 | CYP2C19 (0.83) | CYP2C19BLMPOLBATMACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119290990-A | NFC-based passive portable pesticide detection system and method | 西北大学 | 2025-01-10 | — | — | CN | claimed |
| CN-119224096-A | Multi-pesticide detection method, electrochemical biosensor array and application | 西北大学 | 2024-12-31 | — | — | CN | claimed |
| CN-119000825-A | MXene/gold nanoparticle-based electrochemical modified electrode and application thereof | 辽宁大学 | 2024-11-22 | — | — | CN | claimed |
| CN-118954514-A | MXene-polymerized ionic liquid electrochemical modification material and application thereof | 辽宁大学 | 2024-11-15 | — | — | CN | claimed |
| CN-118425077-A | Intelligent detection device and detection method for toxicological analysis of agricultural product drug residues | 湘南学院 | 2024-08-02 | — | — | CN | claimed |
| CN-118345136-A | Method for synthesizing thymidine diphosphate activated sugar nucleotide | 中国科学院上海药物研究所 | 2024-07-16 | — | — | CN | claimed |
| CN-118206765-A | Preparation method and application of magnetic fluorescent metal organic framework for pesticide residue detection | 郑州大学 | 2024-06-18 | — | — | CN | claimed |
| CN-113834714-B | Detection method for illegally adding orlistat medicine components into traditional Chinese medicine weight-losing health-care products | 广东江门中医药职业学院 | 2024-03-08 | — | — | CN | claimed |
| CN-111850094-B | Cholinesterase determination kit | 武汉中太生物技术有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-117343923-A | Efficient immobilization method of acetylcholinesterase and organophosphorus pesticide degradation monitoring application | 吉林大学 | 2024-01-05 | — | — | CN | claimed |
| CN-1731155-A | Solid enzyme agent for quick detection of residual pesticide toxicity and preparation method and using method thereof | CHINESE ACAD INSP & QUARANTINE (CN) | 2006-02-08 | — | — | CN | claimed |
| CN-1731157-A | Liquid enzyme agent for quick detection of residual pesticide toxicity and preparation method and using method thereof | CHINESE ACAD INSP & QUARANTINE (CN) | 2006-02-08 | — | — | CN | claimed |
| CN-1687756-A | Kit for testing pesticide residue rapidly and use method thereof | UNIV NANJING AGRICULTURAL (CN) | 2005-10-26 | — | — | CN | claimed |
| CN-1560601-A | Portable investigating instrument for food and environment pollutant and its application | 吉林大学 | 2005-01-05 | — | — | CN | claimed |
| CN-2657002-Y | Checking device for organic phosphorus pesticide | UNIV CHINA OCEAN (CN) | 2004-11-17 | — | — | CN | claimed |
| WO-2004085672-A2 | CHEMICAL AGENT ALARM MONITOR | TIAX LLC (US) | 2004-10-07 | — | — | WO | claimed |
| EP-1460135-A1 | Acetylcholinesterase method to detect organophosphorate and carbamate insecticides in water, foods and beverages | Quality Engineering s.r.l. (IT) | 2004-09-22 | — | — | EP | claimed |
| US-6773822-B2 | ANTIFUNGAL AGENT MAY BE PRESENT IN THE GYPSUM CORE AND/OR ON ONE OR BOTH OF THE PAPER FACINGS, AND MAY BE ENCAPSULATED IN A MATERIAL THAT RELEASES THE ANTIFUNGAL AGENT OVER TIME AND/OR UPON EXPOSURE TO MOISTURE. | TEMPLE-INLAND FOREST PRODUCTS CORPORATION | 2004-08-10 | — | — | US | claimed |
| CN-1514237-A | Detecting method of organic phosphorus pesticide and its device | 中国海洋大学 | 2004-07-21 | — | — | CN | claimed |
| US-20040137550-A1 | Acetylcholinesterase assay | LEE HAN LIM (MY) | 2004-07-15 | — | — | US | claimed |