Acetylthiocholine

Acetylthiocholine

SCHEMBL77666

CC(=O)SCC[N+](C)(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 1.00
BLM P54132 2/20 0.95
POLB P06746 1/20 0.95
ATM Q13315 1/20 0.95
ACHE P22303 5/20 0.42
CHRM5 P08912 3/20 0.41
CHRM1 P11229 3/20 0.41
CHRM3 P20309 3/20 0.41
CHRM2 P08172 2/20 0.41
CHRM4 P08173 2/20 0.41
HTR1A P08908 2/20 0.41
CHRNB2 P17787 2/20 0.41
CHRNA7 P36544 2/20 0.41
CHRNA4 P43681 2/20 0.41
SLC6A4 P31645 1/20 0.41
PGR P06401 1/20 0.41
TBXA2R P21731 1/20 0.41
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetylthiocholine SCHEMBL4318613 0.97 CYP2C19 (0.95) CYP2C19BLMPOLBATMACHE
Acetylthiocholine SCHEMBL7172548 0.97 CYP2C19 (0.95) CYP2C19BLMPOLBATMACHE
Acetylthiocholine SCHEMBL400577 0.97 CYP2C19 (0.95) CYP2C19BLMPOLBATMACHE
Acetylthiocholine SCHEMBL16322376 0.97 CYP2C19 (0.95) CYP2C19BLMPOLBATMACHE
Acetylthiocholine SCHEMBL27356791 0.97 CYP2C19 (0.95) CYP2C19BLMPOLBATMACHE
Acetylthiocholine SCHEMBL4318618 0.97 CYP2C19 (0.95) CYP2C19BLMPOLBATMACHE
Acetylthiocholine SCHEMBL1276372 0.97 BLM (1.00) CYP2C19BLMPOLBATMACHE
Acetylthiocholine SCHEMBL9097185 0.91 CYP2C19 (0.83) CYP2C19BLMPOLBATMACHE
Acetylthiocholine SCHEMBL28776641 0.89 CYP2C19 (0.79) CYP2C19BLMPOLBATMACHE
Acetylthiocholine SCHEMBL28172987 0.87 CYP2C19 (0.76) CYP2C19BLMPOLBATMACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1884 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559735-B2 Device for detecting organophosphates PLANTVAX, INC. (US) 2026-02-24 US claimed
US-12558007-B2 In vivo enzyme activity sensors and methods ABBOTT DIABETES CARE INC. (US) 2026-02-24 US claimed
US-20250222141-A1 COMPOSITION FOR THE DETECTION AND PARTIAL DECONTAMINATION OF CHEMICAL THREAT AGENTS ON SKIN SURFACE FOLLOWING DERMAL EXPOSURE THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY 2025-07-10 US claimed
US-20250207170-A1 CARBON CAPTURE IN TWO-STAGE FERMENTATION LANZATECH, INC. 2025-06-26 US claimed
CN-120064229-A Kanamycin sulfate identification fluorescence sensor and kanamycin sulfate detection method 河北大学 2025-05-30 CN claimed
CN-119926495-A High-entropy alloy nano enzyme, biosensor, preparation method and application thereof 重庆医科大学 2025-05-06 CN claimed
CN-119715508-A Method for detecting acetylcholinesterase based on cobalt-doped graphite-phase carbon nitride photoresponse nanoenzyme 济南大学 2025-03-28 CN claimed
EP-4525941-A1 COMPOSITION FOR THE DETECTION AND PARTIAL DECONTAMINATION OF CHEMICAL THREAT AGENTS ON SKIN SURFACE FOLLOWING DERMAL EXPOSURE The Government of The United States, as represented by The Secretary of The Army (US) 2025-03-26 EP claimed
US-20250093270-A1 Method for Detecting Enzyme Activity and Fluorescent Probe Used in Said Method THE UNIVERSITY OF TOKYO (JP) 2025-03-20 US claimed
CN-119574482-A Method for detecting chlorpyrifos by using flower-like vanadium disulfide-based biosensor and application 河南省商业科学研究所有限责任公司 2025-03-07 CN claimed
US-5728374-A BREAKING AND FORMING SULFIDE BONDS IN HAIR HELENE CURTIS, INC. (US) 1998-03-17 US claimed
CN-1115231-A Permanent wave composition and method CURTIS HELENE IND INC (US) 1996-01-24 CN claimed
EP-0672169-A1 BIOSENSOR FOR DETECTION OF AND DISTINGUISHING BETWEEN CHOLINESTERASES INHIBITORS ORITEST S. S R.O. (CZ) 1995-09-20 EP claimed
EP-0667141-A2 Permanent wave composition and method HELENE CURTIS, INC. (US) 1995-08-16 EP claimed
EP-0623146-A1 COMPOUNDS AND METHODS FOR INHIBITING $g(b)-PROTEIN FUNCTION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1994-11-09 EP claimed
US-5338663-A Interferes with formation of specific complex between alpha-antichymotrypsin and beta-protein; hydrolysis of substrate does not occur PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1994-08-16 US claimed
EP-0311492-B1 Kit and immunoassay method applicable to whole cells SANOFI ELF (FR) 1994-03-30 EP claimed
WO-1994005808-A1 BIOSENSOR FOR DETECTION OF AND DISTINGUISHING BETWEEN CHOLINESTERASES INHIBITORS ORITEST S. S R.O. (CZ) 1994-03-17 WO claimed
WO-1993015112-A2 COMPOUNDS AND METHODS FOR INHIBITING β-PROTEIN FUNCTION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1993-08-05 WO claimed
US-4273866-A IMMUNOASSAY FOR QUANTITATIVE ANALYSIS OF ACETYLCHOLINESTERASE ABBOTT LABORATORIES (US) 1981-06-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250093270-A1 Method for Detecting Enzyme Activity and Fluorescent Probe Used in Said Method ACHE, BCHE, SCLY CYP2C19 1420/4885BLM 1463/4885POLB 1144/4885
US-12559735-B2 Device for detecting organophosphates BCHE, LIPE, ACHE CYP2C19 1497/4885BLM 1926/4885POLB 2951/4885
US-12558007-B2 In vivo enzyme activity sensors and methods ACHE, CHAT, BCHE CYP2C19 668/4885BLM 3417/4885POLB 2833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.