Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16406391 | 0.78 | EPHX2 (0.50) | EPHX2POLBHTTHSD17B10ALDH1A1 | |
| SCHEMBL2203168 | 0.74 | POLB (0.54) | EPHX2POLBHTTHSD17B10ALDH1A1 | |
| SCHEMBL235980 | 0.74 | POLB (0.54) | EPHX2POLBHTTHSD17B10ALDH1A1 | |
| SCHEMBL963467 | 0.74 | EPHX2 (0.49) | EPHX2POLBHTTHSD17B10ALDH1A1 | |
| SCHEMBL5178183 | 0.74 | HTT (0.41) | POLBHTTHSD17B10ALDH1A1TDP1 | |
| SCHEMBL4234888 | 0.73 | L3MBTL1 (0.46) | HTTHSD17B10ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL29392684 | 0.71 | DPP4 (0.42) | HTTHSD17B10GRM2HDAC6CD38 | |
| SCHEMBL2348709 | 0.71 | DPP4 (0.42) | HTTHSD17B10GRM2HDAC6CD38 | |
| SCHEMBL231018 | 0.71 | POLB (0.52) | EPHX2POLBHTTHSD17B10ALDH1A1 | |
| SCHEMBL2201618 | 0.71 | POLB (0.52) | EPHX2POLBHTTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |