Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4004677 | 0.89 | KMT2A (0.47) | ALDH1A1LMNAEPHX2ENPP3ENPP1 | |
| SCHEMBL4006598 | 0.89 | NPSR1 (0.41) | ALDH1A1LMNAKMT2AGAAHPGD | |
| SCHEMBL4004804 | 0.89 | KMT2A (0.47) | ALDH1A1LMNAEPHX2ENPP3ENPP1 | |
| SCHEMBL4006094 | 0.88 | EPHX2 (0.47) | ALDH1A1POLBEPHX2HPGDTSHR | |
| SCHEMBL4001738 | 0.88 | EPHX2 (0.47) | ALDH1A1LMNAEPHX2ENPP3ENPP1 | |
| SCHEMBL4006510 | 0.88 | EPHX2 (0.47) | ALDH1A1POLBTP53LMNAEPHX2 | |
| SCHEMBL4002524 | 0.87 | EPHX2 (0.48) | ALDH1A1TP53LMNAEPHX2KMT2A | |
| SCHEMBL4009286 | 0.87 | POLB (0.46) | ALDH1A1POLBTP53LMNAENPP3 | |
| SCHEMBL4307013 | 0.84 | MMP2 (0.39) | ALDH1A1LMNAKMT2ANPSR1TSHR | |
| SCHEMBL4003899 | 0.83 | EPHX2 (0.49) | ALDH1A1LMNAEPHX2KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | claimed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | claimed |