Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.55 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.49 |
| ▸ | GRM5 | P41594 | 8/20 | 0.49 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011353 | 0.93 | PDE10A (0.55) | PDE10APDK4GRM1GRM5CNR1 | |
| SCHEMBL4011635 | 0.89 | PDE10A (0.55) | PDE10APDK4GRM1GRM5GABRP | |
| SCHEMBL4014482 | 0.88 | PDE10A (0.44) | PDE10A | |
| SCHEMBL4007125 | 0.86 | PDE10A (0.56) | PDE10APDK4GRM1GRM5CNR1 | |
| SCHEMBL4013818 | 0.84 | PDE10A (0.55) | PDE10APDK4GRM1GRM5GPR119 | |
| SCHEMBL4009123 | 0.83 | PDE10A (0.53) | PDE10APDK4GRM1GRM5CNR1 | |
| SCHEMBL13770040 | 0.83 | PDE10A (0.60) | PDE10APDK4GRM1GRM5HTR6 | |
| SCHEMBL4013425 | 0.83 | PDE10A (0.62) | PDE10APDK4GRM1GRM5HTR6 | |
| SCHEMBL13769826 | 0.83 | PDE10A (0.69) | PDE10APDK4GRM1GRM5TNK2 | |
| SCHEMBL31040352 | 0.82 | PDK4 (0.59) | PDE10APDK4GRM1GRM5HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |