Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTAFR | P25105 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555950 | 0.92 | PDE10A (0.44) | PDE10ATRPV1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4009241 | 0.88 | PDE10A (0.44) | PDE10ATRPV1ALDH1A1SMN1; SMN2CCNT1 | |
| SCHEMBL4007130 | 0.88 | PDE10A (0.55) | PDE10A | |
| SCHEMBL4017987 | 0.85 | PDE10A (0.45) | PDE10ATRPV1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4009606 | 0.82 | MAPT (0.45) | PDE10AMAPTCCNT1CDK9 | |
| SCHEMBL4007141 | 0.82 | PDE10A (0.42) | PDE10ATRPV1MAPTCCNT1CDK9 | |
| SCHEMBL4015332 | 0.81 | PDE10A (0.51) | PDE10AALDH1A1SMN1; SMN2MAPTCCNT1 | |
| SCHEMBL4014684 | 0.81 | PDE10A (0.56) | PDE10AALDH1A1SMN1; SMN2 | |
| SCHEMBL16992066 | 0.81 | PDE10A (0.46) | PDE10AALDH1A1SMN1; SMN2CCNT1CDK9 | |
| SCHEMBL4013658 | 0.80 | CCNT1 (0.47) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |