SCHEMBL4007231

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4008515	0.89	MAPT (0.80)	MAPTHTTMAPK1AHRPI4KB
	SCHEMBL4886099	0.88	MAPT (0.78)	MAPTHTTMAPK1AHRPI4KB
	SCHEMBL4888050	0.88	MAPT (1.00)	MAPTHTTMAPK1AHRPI4KB
	SCHEMBL14026144	0.87	MAPT (0.77)	MAPTHTTMAPK1AHRPI4KB
	SCHEMBL4891594	0.87	MAPT (0.77)	MAPTHTTMAPK1AHRPI4KB
	SCHEMBL4882141	0.84	MAPT (0.57)	MAPTHTTMAPK1AHRPI4KB
	SCHEMBL4893003	0.84	MAPT (0.57)	MAPTHTTMAPK1AHRPI4KB
	SCHEMBL14026142	0.84	MAPK1 (0.72)	MAPTHTTMAPK1AHRPI4KB
	SCHEMBL4007152	0.84	MAPK1 (0.72)	MAPTHTTMAPK1AHRPI4KB
	SCHEMBL4890194	0.83	MAPT (0.71)	MAPTHTTMAPK1AHRPI4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.