Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 16/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 16/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.65 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13769647 | 0.92 | HTR1A (0.76) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL4012693 | 0.82 | HTR1A (0.52) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL4008507 | 0.81 | HTR1A (0.68) | HTR1ASLC6A2SLC6A4SLC6A3SSTR4 | |
| Trifluoroacetic Acid SCHEMBL4015346 | 0.81 | HTR1A (0.83) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4008496 | 0.80 | HTR1A (0.79) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13770051 | 0.79 | HTR1A (1.00) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| Hydrochloric Acid SCHEMBL4015326 | 0.78 | HTR1A (0.98) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 | |
| Trifluoroacetic Acid SCHEMBL4009081 | 0.78 | HTR1A (0.65) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4009199 | 0.78 | PDE10A (0.51) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13770050 | 0.77 | HTR1A (0.82) | HTR1ASLC6A2SLC6A4SLC6A3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |