Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 19/20 | 0.83 |
| ▸ | SLC6A2 | P23975 | 19/20 | 0.83 |
| ▸ | SLC6A4 | P31645 | 18/20 | 0.83 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.83 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13769626 | 0.91 | HTR1A (1.00) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL4008507 | 0.91 | HTR1A (0.68) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL4007132 | 0.90 | HTR1A (0.98) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4004752 | 0.82 | HTR1A (0.68) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4006184 | 0.81 | HTR1A (1.00) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL4007248 | 0.81 | HTR1A (0.65) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13770273 | 0.81 | HTR1A (0.80) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13769614 | 0.79 | HTR1A (0.76) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13769620 | 0.78 | HTR1A (1.00) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13769768 | 0.78 | HTR1A (1.00) | HTR1ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |